Personal Genome Project

The Personal Genome Project (PGP) is a long-term, large cohort study that aims to sequence and publicize the complete genomes and medical records of thousands of participants in order to enable personal genomics and personalized medicine research. The PGP is creating a freely available scientific resource placed within the public domain, bringing together genomic, environmental and human trait data so that researchers around the world can use it to understand how genes and environment influence each other, as well as to test various hypotheses about the relationships between genotype, environment and phenotype.

In collaboration with the PGP, the NIGMS Human Genetic Cell Repository (HGCR) offers cell lines and DNA samples from many PGP participants. PGP samples are highly characterized, including DNA sequencing data, self-reported medical information, environmental exposures and phenotypic traits. These samples have been consented for commercial use and for public posting of Personally Identifying Genetic Information (PIGI), which allows open-access, public posting of extensive genetic data. Examples of PIGI include whole-genome SNP array data, whole-exome sequences and whole-genome sequences.


Summary Details of NIGMS HGCR PGP Samples

Categories Sub-Categories NIGMS HGCR PGP Samples
Sex Male 95
  Female 40
Race Asian, Other 4
  Black 1
  White 116
  Chinese 2
  Hispanic/Latino 3
  More than 1 race 4
  Not reported 5
Cell Type B-Lymphocyte 131
  Fibroblast 4
  Stem cell 1
  DNA 19

The NIGMS HGCR offers over one hundred PGP samples of various cell types (B-lymphocytes, fibroblasts, iPSCs). PGP samples available include samples from multiple members of the same family and multiple cell types from the same individual.


NIGMS HGCR PGP Samples for Family Studies

Catalog ID Description Cell Type Gender Age (Years) Race Family ID
Relationship to Proband Family Member
GM24385 PERSONAL GENOME PROJECT B-Lymphocyte Male 45 White 3140 Proband 1
GM24143 PERSONAL GENOME PROJECT B-Lymphocyte Female 74 White 3140 Mother 2
GM24149 PERSONAL GENOME PROJECT B-Lymphocyte Male 90 White 3140 Father 3
GM24631 PERSONAL GENOME PROJECT B-Lymphocyte Male 33 Asian, Other 3150 Proband 1
GM24694 PERSONAL GENOME PROJECT B-Lymphocyte Male 64 Chinese 3150 Father 2
GM24695 PERSONAL GENOME PROJECT B-Lymphocyte Female 63 Chinese 3150 Mother 3


Multiple NIGMS HGCR PGP Samples from the Same Subject*

Catalog ID Description Cell Type Gender Age at Collection Race Associated Specimens
GM20431 PERSONAL GENOME PROJECT B-Lymphocyte Male 51 White 2980
GM23248 PERSONAL GENOME PROJECT Fibroblast Male 55 White 2980
GM23338 APPARENTLY HEALTHY NON-FETAL TISSUE Stem Cell Male 55 White 2980
GM21677 PERSONAL GENOME PROJECT B-Lymphocyte Male 42 White 2981
GM23249 PERSONAL GENOME PROJECT Fibroblast Male 44 White 2981
GM21687 PERSONAL GENOME PROJECT B-Lymphocyte Male 52 White 2982
GM23250 PERSONAL GENOME PROJECT Fibroblast Male 44 White 2982
GM21833 PERSONAL GENOME PROJECT B-Lymphocyte Female 46 White 2983
GM23251 PERSONAL GENOME PROJECT Fibroblast Female 50 White 2983

*In response to requests from the scientific research community for multiple cell lines from a single individual, the NIGMS HGCR has assembled a number of collections of multiple cell lines. These cell lines and DNA samples can be found in the “Multiple Cell Lines From the Same Subject” collection. Please see additional information about this collection here.


All NIGMS HGCR PGP Samples Consented for Public Posting of PIGI

See NIGMS HGCR PGP Samples consented for public posting of PIGI here.