research center in the heart of Camden, New Jersey. A Vision for the Future. Starting today. With an initial investment of $30 million over 10 years, the CCRC will leverage existing cancer research in Camden as the foundation to build this work and attract more of the nations brightest minds to the region. CCRC scientists
Dear Science Enthusiasts,Here at Coriell Institute weve had a busy few months preparing for the 2025 Science Fair, which will take place Saturday, March 15 at Rutgers University Camden. Make sure to bookmark /education/science-fair, where you can access Stem Wizard and stay current with important
to investigate the factors that contribute to opioid use disorder (also known as opioid dependence or addiction) and overdose, and how genetic and non-genetic information can be used in the prevention or treatment of this disease.As a leader in the field of personalized medicine, Coriell has a decade of experience in
AdvanceYou can enter DVSF if:You are an individual project in 6-8th grades and won 1st or 2ndYou are a team project in 6-8th grades and won 1st or 2nd You are an individual project in 9-12th grades and won 1st, 2nd, or 3rdYou are a team project in 9-12th grades and won 1st, 2nd, or 3rdCoriell will automatically register you by
committee, Coriell might be able to approve the student's work. Please contact us with any questions.How can I prepare for the judge interview portion?In addition to the overall strength of a student's project and the development of an effective project tri-fold board judges also evaluate the student's interview
Welcome teachers and sponsors! This section is intended to help guide you through the fair process. As a registered teacher/sponsor, you are able to review and manage all projects associated with your account.Registering as a Teacher/SponsorIf you are interested in becoming a sponsor, please reach out to us at
Welcome teachers and sponsors! This section is intended to help guide you through the fair process. As a registered teacher/sponsor, you are able to review and manage all projects associated with your account.Registering as a Teacher/SponsorIf you are interested in becoming a sponsor, please reach out to us at
Participation in the Coriell Institute Science Fair is managed through STEM Wizard. Registration is designed to streamline the submission process. With just a few simple clicks, you'll be able to create an account and download all the required forms.Follow these instructions to create a student account with STEM
Dear Science Enthusiasts,Here at Coriell Institute weve had a busy few months preparing for the 2025 Science Fair, which will take place Saturday, March 15 at Rutgers University Camden. Make sure to bookmark /education/science-fair, where you can access Stem Wizard and stay current with important
for your basic contact information will appear.IMPORTANT TIPS:If using a school email address, be sure that it can receive emails from stemwizard.com. Otherwise, use a personal email address.If you want to allow STEM wizard to send SMS/text messages, check the box to allow SMS/text messages and enter a cell phone
with the reversible nature of the biochemical modifications required for epigenetics led to the field of epigenetic therapy, which aims to reprogram gene expression to achieve a therapeutic effect.This Epigenetic Therapies SPORE encompasses four major themes: Develop and test drugs against new epigenetic targets
to investigate the factors that contribute to opioid use disorder (also known as opioid dependence or addiction) and overdose, and how genetic and non-genetic information can be used in the prevention or treatment of this disease.As a leader in the field of personalized medicine, Coriell has a decade of experience in
for immune checkpoint therapy response. Mechanics and sequelae of response to DNMTi may be dependent on mutation status of the tumor suppressor TP53, with missense mutations associated with a NFKB-mediated inflammasome response compared to the type 1 interferon response observed in TP53-wildtype NSCLC. In vitro 2D and 3D
potential conflicts for judging. Having a conflict does not preclude you from judging, it simply helps us create the fairest judging assignments. 3. Judge Assignment QuestionsWe do our best to match judges with a category of their preference, so in this milestone you can let us know which areas you are most comfortable with
name, use this document as a reference.3. Files and Forms Due February 23, 2025 (11PM)a. How to identify which ISEF forms required for your project:The first time you enter the Files and Forms milestone, you will complete the ISEF Rules Wizard to identify which ISEF forms you need to submit for your project by clicking
such as DNA methyltransferase inhibitors, can reactivate silenced RE in cancer cells. These reactivated REs act as viral mimics and activate toll-like receptors (TLRs) and interferon (IFN) pathways in these cells. As a result, cancer cells with reactivated REs become more immunogenic by expressing viral mimicries5, which
plan and conclusion with supporting data reflect the student's mastery of the subject matter, and also demonstrate creativity and a passion for science!Standard-sized tri-folds are 36 tall and 48" wide and can be purchased at several retail stores in the area (Michael's, Staples, A.C. Moore).For more helpful
Presentation Room. There will be a 1-hour window for Student Check-In and to Set up projects starting at 7:30 a.m. the morning of the Fair, for students who cannot complete Check-In/Set Up on 3/14. Final Check-Ins Need to occur before 8:15 a.m on 3/15. On Fair day, participants will meet with judges to discuss their projects in
appreciate your time and your support of local student scientists!It is with the safety of these student scientists in mind, that Coriell requires any volunteer who has direct contact with a minor through our Institution to pass a background check. We appreciate your cooperation in advance.We have assembled some helpful
SPORE Principal InvestigatorsJean-Pierre Issa, MDCoriell Institute for Medical ResearchPresident & CEO403 Haddon Ave, Camden NJ856-966-7377jpissa@coriell.orgStephen B. Baylin, MDVan Andel InstituteProfessor333 Bostwick Ave, Grand Rapids MI616-234-5000sbaylin@jhmi.eduPeter A. Jones, PhD, DSc (hon.)Van Andel
The Form Uploader is only able to be used by students. However, teachers do have two different options on how to upload files and forms for students.To reflect a Teacher/Sponsor upload, follow these steps:Log into your account.Go to the Student Management Tab. All student accounts linked with you will appear here
view or send direct messages. All Messages sent through STEM Wizard are forwarded to the student and teacher/sponsor email addresses associated with the project.Messaging within STEM Wizard can be a helpful tool for you to utilize if your registered teacher/sponsor is not someone you meet with regularly. It allows you to
Important Dates and Deadlines page.Understanding milestone symbols:When you have not completed a milestone, it will be marked with an orange exclamation point. All milestones will initially appear this way.When you complete a milestone that needs to be approved by your administrator, it will turn to the orange hourglass symbol
Forms 1, 1A, a Research Plan, and 1B.For access to ISEF Forms: ISEF Forms LinkAdditional FormsProjects with additional risks, such as human subjects, vertebrate animals, and potentially hazardous materials like chemicals and animal tissue, require additional forms as do continuation projects. All forms must be completed
In addition to 1st and 2nd place presented to students in each age group and category, several sponsors of the 44nd Annual Coriell Institute Science Fair have provided special and distinctive awards to recognize students (both individuals and teams) who have displayed excellence with their science fair projects
Returning to an in-person event is exciting because it allows for more engagement - however, our experience with the previous two virtual fairs has allowed us to advance our technology and to refine our procedures to allow students, teachers, and judges greater access to information.Therefore, in addition to the
The Coriell Institute is grateful for the sponsors who make the Science Fair possible. Click here to become a sponsor and learn more.
Please keep in mind that all deadlines are at 11:00 p.m. EST on the dates listed below. Unfortunately, we will not be accepting any late submissions.* Note: You must register and submit all forms, research plan, and project details through Coriell's Science Fair platform, STEM Wizard.
Throughout its rich history, the Coriell Institute Science Fair has always relied on the contributions of outstanding volunteer judges. Our Fair draws the best and brightest students from all across South Jersey, and in turn we recruit the best and brightest experts to help judge the myriad of project submissions. We
Square Title: Age-dependent alterations in the human striatum identify a PPP1R15B-miR-196a node as a modier of Huntingtons disease phenotypes Samples Used: AG13369, AG08379, AG06858Hamam et al. 2024 in Research Square Title: Cell growth and mitochondrial anomalies in induced pluripotent stem cells with Presenilin 1
encephalopathy. Ann Neurol 2015, 78(2):323-328. PMC4646089Georges P, Boissart C, Poulet A, Peschanski M, Benchoua A: Protein Kinase-A Inhibition Is Sufficient to Support Human Neural Stem Cells Self-Renewal. Stem Cells 2015, 33(12):3666-3672.Gray NE, Quinn JF: Alterations in mitochondrial number and function in Alzheimer's disease
15592294.2022.2160568. Epub ahead of print. PMID: 36572998.Sun A, Park P, Cole L, Vaidya H, Maegawa S, Keith K, Calendo G, Madzo J, Jelinek J, Jobin C, Issa JJ.Safety, Outcomes, and T-Cell Characteristics in Patients with Relapsed or Refractory MDS or CMML Treated with Atezolizumab in Combination with GuadecitabineClinical Cancer Research
, Progressive Muscular Atrophy, Primary Lateral Sclerosis and Progressive Bulbar Palsy. The Repository also banks subjects with MNDs that have known genetic causes, including Spinal Bulbar Muscular Atrophy (Kennedys Disease) and Spinal Muscular Atrophy. Also included in the collection are unaffected (At Risk) and affected blood
Investigators who wish to share cell lines or DNA samples from the NHGRI Repository with other investigators must read the statement below and contact the Repository before ordering or transferring samples to a collaborator.Genetic research often involves collaborations among several investigators or several
shipping materials, and a pre-paid FedEx return shipping label. Please review the following Collection and Shipping Instructions in advance of your appointment. You may bring them with you to your appointment as reference for your doctor. Blood sample (for domestic or international families)Biopsy sample Schedule an exam with
As Coriells Director of External Affairs, Haskell Berman is responsible for building and maintaining relationships with external partners, as well as engaging with local, state and federal policymakers and government entities. Haskell brings more than 37 years of state government, political, and public affairs
should be collected in duplicate tubes (approximately 8 ml each) in acid citrate dextrose solution A (ACD) to prevent clotting (yellow-topped tube). Biopsy specimens should be placed in a T25 tissue culture flask or screw-top vial with culture medium containing 100 units/ml of penicillin and 100 micrograms/ml of
Scientists working in the CCRC are investigating the basic biology of cancer and translating that knowledge into new and improved therapeutics for patients. Theses partners have pledged an initial $30 million to fund this center over 10 years. Camden Opioid Research InitiativeAt the end of 2018, we launched a multi-prong
Scientists working in the CCRC are investigating the basic biology of cancer and translating that knowledge into new and improved therapeutics for patients. Theses partners have pledged an initial $30 million to fund this center over 10 years. Camden Opioid Research InitiativeAt the end of 2018, we launched a multi-prong
Giving FAQsCan I make a gift online?Yes, you can give quickly and securely online with a credit card.Where do I send my gift?You can send your gift of cash, check, or money order may be made payable to Coriell Institute for Medical Research to 403 Haddon Avenue, Camden, New Jersey 08103.How do I make a credit card
Each investigator must have his/her own Assurance Form on file.This form is not electronic. You will need to sign a paper copy, and email this to customerservice@coriell.org before your order can be processed.Each order placed with the Repository must be placed electronically using our online catalog system. The
cellular and developmental biology. 2018. PMID: 315522492017A novel isoform of TET1 that lacks a CXXC domain is overexpressed in cancer.Good, Charly R.; Madzo, Jozef; Patel, Bela; Maegawa, Shinji; Engel, Nora; Jelinek, Jaroslav; Issa, Jean-Pierre J. Nucleic acids research. 2017. PMID: 31552249Sex chromosomes drive gene
Shumei Song, MD, PhDProfessorI am a Professor in Coriell Institute for Medical Research in Camden, New Jersey. I received my PhD in Molecular Biology and Biochemistry from Beijing Cancer Institute, Beijing University, China where my graduate work focus on the cloning and elucidating the functional role of the VEGF
MC180295 is a highly potent and selective CDK9 inhibitor with preclinical in vitro and in vivo efficacy in cancerZhang H, Huang C, Gordon J, Yu S, Morton G, Childers W, Abou-Gharbia M, Zhang Y, Jelinek J, Issa JJ.Clin Epigenetics. 2024 Jan 3;16(1):3. doi: 10.1186/s13148-023-01617-3. PMID: 38172923; PMCID:PMC10765884
Federal Express with second day delivery guaranteed.SHIPMENT OF CELL CULTURESStem cell plastic ampoules will be shipped frozen in dry ice. In certain situations, at the discretion of the NIA Repository, stem cells may be shipped as growing cultures.DESCRIPTIVE DATAEach shipment will include a packing slip and information
investigator must agree to the NIA Repository Stem Cell Replacement Policy, stated below: There are no replacements for stem cell cultures, except for under the following circumstances: The cultures arrive physically compromised at their destination (e.g., not frozen, broken ampoule) and a replacement is requested within 24 hours
Agreement (MTA) and Statement of Research Intent (SORI)Coriell Cell Repositories403 Haddon AvenueCamden, New Jersey 08103Telephone: 800-752-3805 in the USA856-757-4848 from other countriescustomerservice@coriell.orgPublicationsRecipient will acknowledge Provider in any publication that contains data or information about the
Tourette SyndromeTourette Syndrome is a neurological disorder characterized by tics. Tics are repetitive, involuntary movements and vocalizations. The types and severity of tics are variable and can include eye blinking, shoulder shrugging, throat clearing , yelping, and hitting oneself. Symptoms are first noticed in
care to patients with movement disorders, to investigate better treatment and diagnostic tools, and to develop prevention strategies.PD Society Brain Bank articles regarding Parkinsonism:What features improve the accuracy of clinical diagnosis in Parkinson's disease: a clinicopathologic study. 1992.Accuracy of clinical
The study of epigenomics is a core part of our mission at the Coriell Institute for Medical Research.Epigenomics is the study of the sum of epigenetic modifiers that work on top of genetics. Chemical compounds added to DNA act as instructions what genes are expressed or silent in a given cell type. Cells in our body
Our mission is to prevent and cure disease through biomedical research.
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