Title: Zinc controls PML nuclear body formation through regulation of a paralog specific auto-inhibition in SUMO1
Samples Used: I90
Title: Activation of the JNKs/ATM-p53 axis is indispensable for the cytoprotection of dermal fibroblasts exposed to UVB radiation
Samples Used: AG01523
Title: Role of the cystathionine β-synthase / H2S pathway in the development of cellular metabolic dysfunction and pseudohypoxia in down syndrome
Samples Used: AG07096 AG05397
Title: APOE4-carrying human astrocytes oversupply cholesterol to promote neuronal lipid raft expansion and Aβ generation
Samples Used: AG09173
Title: Bonding antimicrobial rhamnolipids onto medical grade PDMS: A strategy to overcome multispecies vascular catheter-related infections
Samples Used: AG22719
Title: N-oleoylethanolamide treatment of lymphoblasts deficient in Tafazzin improves cell growth and mitochondrial morphology and dynamics
Samples Used: AG15022 AG14731 AG14948 AG14750 AG14947
Title: Comparison of Endemic and Epidemic Vesicular Stomatitis Virus Lineages in Culicoides sonorensis Midges
Samples Used: AG08113
Title: miR-376a-3p and miR-376b-3p overexpression in Hutchinson-Gilford progeria fibroblasts inhibits cell proliferation and induces premature senescence
Samples Used: AG11513 AG11498 AG08498 AG07095 AG08471
Title: MPTAC links alkylation damage signaling to sterol biosynthesis
Samples Used: AG14953
Title: Detection of Pathological Markers of Neurodegenerative Diseases following Microfluidic Direct Conversion of Patient Fibroblasts into Neurons
Samples Used: AG11732 AG04062 AG04060 AG04148 AG07141 AG07801 AG09602 AG08711 AG06848 AG06840 AG20442 AG20446 AG20443 AG08395
Title: ATase inhibition rescues age-associated proteotoxicity of the secretory pathway
Title: Salt-Inducible Kinase 1 is a potential therapeutic target in Desmoplastic Small Round Cell Tumor
Samples Used: AG07086
Title: Compound screen identifies the small molecule Q34 as an inhibitor of SARS-CoV-2 infection
Samples Used: AG06869
Title: Combination of Melatonin and Small Molecules Improved Reprogramming Neural Cell Fates via Autophagy Activation
Samples Used: AG08379 AG09019
Title: New bioactive 5-arylcarboximidamidopyrazolo[3,4-c]pyridines: Synthesis, cytotoxic activity, mechanistic investigation and structure-activity relationships
Samples Used: AG01523
Title: STING regulates peripheral nerve regeneration and colony stimulating factor 1 receptor (CSF1R) processing in microglia
Samples Used: AG09429
Title: The multicellular signalling network of ovarian cancer metastases
Samples Used: AG07086
Title: Inactivity of peptidase ClpP causes primary accumulation of mitochondrial disaggregase ClpX with its interactors at the nucleoid and RNA granule
Samples Used: AG06103 AG02261 AG06858
Title: Ultraviolet Radiation Protection Potentials of Methylene Blue for Human Skin and Coral Reef Health
Samples Used: AG09266 AG11695 AG08434 AG11725
Title: Down-syndrome-induced senescence disrupts the nuclear architecture of neural progenitors
Samples Used: AG05397 AG06922
Title: Accumulation of APP-CTF induces mitophagy dysfunction in the iNSCs model of Alzheimer’s disease
Samples Used: AG09035
Title: Novel patient-derived models of desmoplastic small round cell tumor confirm a targetable dependency on ERBB signaling
Samples Used: AG07086
Title: Human pluripotent stem cell-derived functional sympathetic neurons express ACE2 and RAAS components: a framework for studying the effect of COVID-19 on sympathetic responsiveness
Samples Used: AG02602
Title: Endotype reversal as a novel strategy for screening drugs targeting familial Alzheimer’s disease
Samples Used: AG06840
Title: A Rare Mutation in LMNB2 Associated with Lipodystrophy Drives Premature Cell Senescence
Samples Used: AG09309
Title: In vivo base editing rescues Hutchinson–Gilford progeria syndrome in mice
Samples Used: AG03257
Title: Systematic screening identifies therapeutic antisense oligonucleotides for Hutchinson–Gilford progeria syndrome
Samples Used: AG06297
Title: Trisomy 21 impairs PGE2 production in dermal fibroblasts
Samples Used: AG07438 AG05024 AG07095 AG06922 AG10803 AG08942 AG06103
Title: Nuclear Transport Factor 2 (NTF2) suppresses WM983B metastatic melanoma by modifying cell migration, metastasis, and gene expression
Samples Used: AG21857
Title: Non-human primate adenoviruses of the Human Adenovirus B species are potent and broadly-acting oncolytic vector candidates
Samples Used: AG05965
Title: Novel patient-derived models of DSRCT enable validation of ERBB signaling as a potential therapeutic vulnerability
Samples Used: AG07086
Title: Genome-wide screening in human kidney organoids identifies developmental and disease-related aspects of nephrogenesis
Samples Used: AG09429
Title: Non-invasive prenatal screening for foetal trisomy: An assessment of reliability and reporting
Samples Used: AG09387 AG09394
Title: Cellular Senescence limits Translational Readthrough
Samples Used: I90
Title: Acquired Radioresistance in Cancer Associated Fibroblasts is Concomitant with Enhanced Antioxidant Potential and DNA Repair Capacity
Samples Used: AG01522
Title: Investigating spatial fractionation and radiation induced bystander effects: a mathematical modelling approach
Samples Used: AG01522
Title: Generation of gene edited hiPSC from familial Alzheimer's disease patient carrying N141I missense mutation in presenilin 2
Samples Used: AG09908
Title: Modeling Sporadic Alzheimer’s Disease in Human Brain Organoids under Serum Exposure
Samples Used: AG06869, AG14048, and AG10884
Title: Cellular junction and mesenchymal factors delineate an endometriosis-specific response of endometrial stromal cells to the mesothelium
Samples Used: AG07086
Title: High concordance in preimplantation genetic testing for aneuploidy between automatic identification via Ion S5 and manual identification via Miseq
Samples Used: AG12070
Title: N-Acetylcysteine prevents amyloid-β secretion in neurons derived from human pluripotent stem cells with trisomy 21
Samples Used: AG06892
Title: Stable maintenance of the Mre11-Rad50-Nbs1 complex is sufficient to restore the DNA double-strand break response in cells lacking RecQL4 helicase activity
Samples Used: AG09173
Title: APOE4-carrying human astrocytes oversupply cholesterol to promote neuronal lipid raft expansion and Aβ generation
Samples Used: AG09173
Title: ZNF768 links oncogenic RAS to cellular senescence
Samples Used: I90-10
Title: Off-the-shelf proximity biotinylation for interaction proteomics
Samples Used: AG08469
Title: Generation of inducible pluripotent stem cell lines from Alzheimer’s disease patients with APOE e3/e3 genotype
Samples Used: AG10039 and AG08242
Title: CD147 mediates the CD44s-dependent differentiation of myofibroblasts driven by transforming growth factor-β1
Samples Used: AG02262
Title: Novel method of real-time PCR-based screening for common fetal trisomies
Samples Used: AG05121, AG11552, AG07167, AG0801, and AG12070
Title: Genotoxic stress in constitutive trisomies induces autophagy and the innate immune response via the cGAS-STING pathway
Samples Used: AG04392 and AG21708
Title: Impacts of Infectious Dose, Feeding Behavior, and Age of Culicoides sonorensis Biting Midges on Infection Dynamics of Vesicular Stomatitis Virus
Samples Used: AG08113
Title: NF-κB/IKK activation by small extracellular vesicles within the SASP
Samples Used: AG16086, AG06240, AG13152, and AG13222
Title: Progerin impairs 3D genome organization and induces fragile telomeres by limiting the dNTP pools
Samples Used: AG06297, AG11498, and AG11513
Title: BING, a novel antimicrobial peptide isolated from Japanese medaka plasma, targets bacterial envelope stress response by suppressing cpxR expression
Samples Used: AG06858
Title: A deep learning approach to identify gene targets of a therapeutic for human splicing disorders
Samples Used: AG16409
Title: Co-development of central and peripheral neurons with trunk mesendoderm in human elongating multi-lineage organized gastruloids
Samples Used: AG08498
Title: FOXM1 repression increases mitotic death upon antimitotic chemotherapy through BMF upregulation
Samples Used: AG10884
Title: Generation of six human iPSC lines from patients with a familial Alzheimer’s disease (n = 3) and sex- and age-matched healthy controls (n = 3)
Samples Used: AG06840, AG06848, and AG09908
Title: The nucleoplasmic interactions among Lamin A/C-pRB-LAP2α-E2F1 are modulated by dexamethasone
Samples Used: AG09429
Title: Human WRN is an intrinsic inhibitor of progerin, abnormal splicing product of lamin A
Samples Used: AG09603 and AG05229
Title: Macrophage Plasticity and Function in the Lung Tumour Microenvironment Revealed in 3D Heterotypic Spheroid and Explant Models
Samples Used: AG02603
Title: G-quadruplexes originating from evolutionary conserved L1 elements interfere with neuronal gene expression in Alzheimer’s disease
Samples Used: AG04152, AG09602, AG08243, and AG08259
Title: Statins as a Therapeutic Approach for the Treatment of Pseudoxanthoma Elasticum Patients: Evaluation of the Spectrum Efficacy of Atorvastatin In Vitro
Samples Used: AG13145, AG11482, and AG14284
Title: Mitovesicles are a novel population of extracellular vesicles of mitochondrial origin altered in Down syndrome
Samples Used: AG07095
Title: A small-molecule ICMT inhibitor delays senescence of Hutchinson-Gilford progeria syndrome cells
Samples Used: GM01972, AG03513, AG03258, and AG03512
Title: Fibroblasts from idiopathic Parkinson’s disease exhibit deficiency of lysosomal glucocerebrosidase activity associated with reduced levels of the trafficking receptor LIMP2
Samples Used: AG11743, AG06959, AG04061, AG13220, AG04355, AG11489, AG07141, AG05265, AG06010, AG06241, AG06281, AG20439, and AG20445
Title: Might Fibroblasts from Patients with Alzheimer’s Disease Reflect the Brain Pathology? A Focus on the Increased Phosphorylation of Amyloid Precursor Protein Tyr682 Residue
Title: Progerinin, an optimized progerin-lamin A binding inhibitor, ameliorates premature senescence phenotypes of Hutchinson-Gilford progeria syndrome
Samples Used: AG03198, AG11513, AG11498, AG03199, and AG00038
Title: Establishment human induced pluripotent stem cell line from idiopathic non-familial Parkinson’s disease patient using self-replicating RNA vector
Samples Used: AG20442
Title: Centrosome and ciliary abnormalities in fetal akinesia deformation sequence human fibroblasts
Samples Used: AG05965 and AG01972
Title: SAMMY-seq reveals early alteration of heterochromatin and deregulation of bivalent genes in Hutchinson-Gilford Progeria Syndrome
Samples Used: AG08498 and AG07095
Title: Exploring the potential of chitosan-based particles as delivery-carriers for promising antimicrobial glycolipid biosurfactants
Samples Used: AG22719
Title: Prolonged Glucocorticoid Exposure Does Not Accelerate Telomere Shortening in Cultured Human Fibroblasts
Samples Used: I90-83
Title: LSH mediates gene repression through macroH2A deposition
Samples Used: AG06814
Title: Large-Scale Topological Changes Restrain Malignant Progression in Colorectal Cancer
Samples Used: AG06814
Title: Oxidative cross-linking of fibronectin confers protease resistance and inhibits cellular migration
Samples Used: I90
Title: Modeling Human Cytomegalovirus-Induced Microcephaly in Human iPSC-Derived Brain Organoids
Samples Used: AG14048 and I90-10
Title: Lowered Cyclin E levels increase the efficiency and the specificity of capsaicin against
cancerous cells of mesothelium
Samples Used: AG07086
PDF available: here
Title: Generation of human control iPSC line CHOPi004-A from juvenile foreskin fibroblast cells
Samples Used: AG07095
Title: A method for differentiating human induced pluripotent stem cells toward functional cardiomyocytes in 96-well microplates
Samples Used: AG05836
Title: ESCRT-III controls nuclear envelope deformation induced by progerin
Samples Used: AG03512 and AG11513
Title: WRN modulates mRNA translation by influencing mRNA export from the nucleus through its interaction with the export receptor NXF1 in HeLa cancer cell
Samples Used: AG06814
Title: PAI-1-Dependent Inactivation of SMAD4-Modulated Junction and Adhesion Complex in Obese Endometrial Cancer
Samples Used: AG17870
Title: PICALM Rescues Endocytic Defects Caused by the Alzheimer’s Disease Risk Factor APOE4
Samples Used: AG07086
Title: Ascites-induced compression alters the peritoneal microenvironment and promotes metastatic success in ovarian cancer
Samples Used: AG07086
Title: Vulnerability of progeroid smooth muscle cells to biomechanical forces is mediated by MMP13
Samples Used: AG01972 and AG06917
Title: Nucleolar disruption, activation of P53 and premature senescence in POLR3A-mutated Wiedemann-Rautenstrauch syndrome fibroblasts
Samples Used: AG01972
Title: Lamin A‐mediated nuclear lamina integrity is required for proper ciliogenesis
Samples Used: AG01972, AG08466, AG11513, AG06297, AG06917, AG03512, and AG03257
Title: Biological Aging Modulates Cell Migration via Lamin A/C-Dependent Nuclear Motion
Samples Used: AG09558 and AG09602
Title: Highly accurate skin-specific methylome analysis algorithm as a platform to screen and validate therapeutics for healthy aging
Samples Used: AG08434 and AG11725
Title: Novel resveratrol derivatives have diverse effects on the survival, proliferation and senescence of primary human fibroblasts
Samples Used: AG05965
Title: Apolipoprotein D-mediated preservation of lysosomal function promotes cell survival and delays motor impairment in Niemann-Pick type A disease
Samples Used: AG07323
Title: Lysosome Associated Protein Transmembrane 4B (LAPTM4B)-24 is the predominant protein isoform in human tissues and undergoes rapid, nutrient-regulated turnover
Samples Used: AG08498
Title: Cytoskeleton stiffness regulates cellular senescence and innate immune response in Hutchinson–Gilford Progeria Syndrome
Samples Used: AG03513, AG06917,AG08466, AG08468, AG08469, and AG08470
Title: Fully Phased Sequence of a Diploid Human Genome Determined de Novo from the DNA of a Single Individual
Samples Used: AG06814
Title: Generation of human induced pluripotent stem cell line from Alzheimer’s disease patient with PSEN2 N141I mutation using integration-free non-viral method
Samples Used: AG09908
Title: Reacquisition of a spindle cell shape does not lead to the restoration of a youthful state in senescent human skin fibroblasts
Samples Used: AG05397
Title: Reacquisition of a spindle cell shape does not lead to the restoration of a youthful state in senescent human skin fibroblasts
Samples Used: AG16086, AG06240, AG13152, AG13222, AG11572, AG06917, AG07493, and AG10677
Title: Reacquisition of a spindle cell shape does not lead to the restoration of a youthful state in senescent human skin fibroblasts
Samples Used: AG01523
Title: Repetitive elements as a transcriptomic marker of aging: Evidence in multiple datasets and models
Samples Used: AG09843 and AG11748
Title: Pathogenic variants in EP300 and ANKRD11 in patients with phenotypes overlapping Cornelia de Lange syndrome
Samples Used: AG09393 and AG14730
Title: Naked mole-rat very-high-molecular-mass hyaluronan exhibits superior cytoprotective properties
Samples Used: I90-78
Title: Restoration of lysosomal function after damage is accompanied by recycling of lysosomal membrane proteins
Samples Used: AG01518
Title: BCL-xL/BCL2L1 is a critical anti-apoptotic protein that promotes the survival of differentiating pancreatic cells from human pluripotent stem cells
Samples Used: AG16102
Title: Impaired Myofibroblast Dedifferentiation Contributes to Non-Resolving Fibrosis in Aging
Samples Used: I90-83 and I90-53
Title: Bioprospecting Sponge-Associated Marine Cyanobacteria to Produce Bioactive Compounds
Samples Used: AG01523
Title: Hydrogen Peroxide Mediates Artemisinin-Derived C-16 Carba-Dimer-Induced Toxicity of Human Cancer Cells
Samples Used: AG01522
Title: Unraveling LMNA Mutations in Metabolic Syndrome: Cellular Phenotype and Clinical Pitfalls
Samples Used: AG07095 and AG09309
Title: Human-Induced Neurons from Presenilin 1 Mutant Patients Model Aspects of Alzheimer's Disease Pathology
Samples Used: AG09429, AG02262, AG08711, AG08270, and AG08446
Title: Cancer cell-intrinsic function of CD177 in attenuating β-catenin signaling
Samples Used: AG11132
Title: Defective Mitochondrial Pyruvate Flux Affects Cell Bioenergetics in Alzheimer’s Disease-Related Models
Samples Used: AG09908, AG08525, AG08269, and AG09173
Title: Hyaluronidase-2 Regulates RhoA Signalling, Myofibroblast Contractility and other Key Pro-fibrotic Myofibroblast Functions
Samples Used: AG02262
Title: Persistent DNA damage triggers activation of the integrated stress response to promote cell survival under nutrient restriction
Samples Used: AG09319 and AG16409
Title: Activin A-Mediated Regulation of XT-I in Human Skin Fibroblasts
Samples Used: AG14284 and AG13145
Title: PRMT5 silencing selectively affects MTAP-deleted mesothelioma: In vitro evidence of a novel promising approach
Samples Used: AG07086
Title: Genetic correction of Werner syndrome gene reveals impaired pro-angiogenic function and HGF insufficiency in mesenchymal stem cells
Samples Used: AG00780
Title: Dysregulation of the retromer complex system in Down syndrome
Samples Used: AG04823 and AG08498
Title: Venereal Transmission of Vesicular Stomatitis Virus by Culicoides sonorensis Midges
Samples Used: AG08113
Title: Novel and prevalent non-East Asian ALDH2 variants; Implications for global susceptibility to aldehydes’ toxicity
Samples Used: AG07123
Title: A nuclear lamina‐chromatin‐Ran GTPase axis modulates nuclear import and DNA damage signaling
Samples Used: AG01972, AG11498, AG03199 and AG08469
Title: Predicting age from the transcriptome of human dermal fibroblasts
Samples Used: AG08498, AG13153, AG12207, AG13234, AG14251, AG12587, AG13144, AG16102, AG13967, AG16358, AG04386, AG13066, AG04457, AG04063, AG05413, AG16409, AG11745, AG04661, AG11698, AG05274, AG13244, AG06276, AG11484, AG11725, AG11162, AG11730, AG11556, AG11744, AG12954, AG12947, AG11154, AG04143, AG12989, AG09843, AG13962, AG11748, AG12493, AG13349, AG12602, AG04662, AG05247, AG05248, AG10884, AG11732, AG11017, AG11808, AG09975, AG13225, AG04065, AG11735, AG11357, AG06308, AG12597, AG13129, AG07124, AG12588, AG13208, AG09860, AG13065, AG06291, AG04461, AG12788, AG09559, AG07725, AG04054, AG12599, AG04064, AG07478, AG13018, AG09602, AG16086, AG08433, AG09599, AG04059 and AG09605
Title: ATM activation is impaired in human cells defective in RecQL4 helicase activity
Samples Used: AG17524
Title: Frenolicin B Targets Peroxiredoxin 1 and Glutaredoxin 3 to Trigger ROS/4E-BP1-Mediated Antitumor Effects
Samples Used: I91L-16 and AG06173
Title: A disease causing ATLASTIN 3 mutation affects multiple endoplasmic reticulum-related pathways
Samples Used: AG13334 and AG04151
Title: Autophagic cell death restricts chromosomal instability during replicative crisis
Samples Used: AG06814-N
Title: Fibrin-Targeted Polymerized Shell Microbubbles as Potential Theranostic Agents for Surgical Adhesions
Samples Used: AG07086
Title: REST and Neural Gene Network Dysregulation in iPSC Models of Alzheimer’s Disease
Samples Used: AG04455, AG08125, AG08379, AG08509, AG14244, AG09173, AG06869, AG07376, AG21158,
Title: Extranuclear DNA accumulates in aged cells and contributes to senescence and inflammation
Samples Used: AG04392, AG04433, AG04525, AG06555, AG02496, AG03058, AG04405, AG10578, AG11513,
Title: Chromosome alignment maintenance requires the MAP RECQL4, mutated in the Rothmund–Thomson
syndrome
Samples Used: AG05013 and AG18371
Title: Corticosteroids inhibit Mycobacterium tuberculosis-induced necrotic host cell death by abrogating
mitochondrial membrane permeability transition
Samples Used: AG05965
Title: Familial Alzheimer’s disease-linked presenilin mutants and intracellular Ca2+ handling: A single-organelle,
FRET-based analysis
Samples Used: AG09908, AG08525, AG06840 and AG08539
Title: Progerin accelerates atherosclerosis by inducing endoplasmic reticulum stress in vascular smooth muscle
cells
Samples Used: AG06297
Title: Analysis of somatic mutations identifies signs of selection during the in vitro aging of primary dermal
fibroblasts
Samples Used: AG13077, AG08433, AG10579 and AG07091
Title: A pleiotropic role for exosomes loaded with the amyloid β precursor protein carboxyl-terminal fragments in
in the brain of Down syndrome patients
Samples Used: AG06922 and AG07095
Title: mTOR hyperactivation in Down Syndrome underlies deficits in autophagy induction, autophagosome
formation, and mitophagy
Samples Used: AG06922, AG07095, AG07096 and AG04823
Title: Sp1 phosphorylation by ATM downregulates BER and promotes cell elimination in response to persistent
DNA damage
Samples Used: AG06173
Title: Everolimus rescues multiple cellular defects in laminopathy-patient fibroblasts
Samples Used: AG04110
Title: SCAMP4 enhances the senescent cell secretome
Samples Used: AG04110
Title: Meganuclease targeting of PCSK9 in macaque liver leads to stable reduction in serum cholesterol
Samples Used: AG07095
Title: Disease-associated short tandem repeats co-localize with chromatin domain boundaries
Samples Used: AG06103
Title: Landscape of the complete RNA chemical modifications in the human 80S ribosome
Samples Used: AG04645 and AG03738
Title: Replication stress shapes a protective chromatin environment across fragile genomic regions
Samples Used: I90-15
Title: Merkel cell polyomavirus infection of animal dermal fibroblasts
Samples Used: AG05308, AG05356, and AG06116
Title: LONGO: an R package for interactive gene length dependent analysis for neuronal identity
Samples Used: AG04148
Title: Increased MMP activity in curved geometries disrupts the endothelial cell glycocalyx creating a
proinflammatory environment
Samples Used: AG09799
