GM17019
LCL from B-Lymphocyte
Description:
HUMAN VARIATION PANEL - CHINESE (VERSION 1)
HUMAN VARIATION PANEL - CHINESE (VERSION 2)
SNP500 PANEL
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Repository
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NIGMS Human Genetic Cell Repository
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| Subcollection |
Human Variation
GeT-RM Samples
Pharmacogenetics |
| Alternate IDs |
GM11324 [HUMAN VARIATION PANEL - CHINESE (VERSION 1)] |
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Biopsy Source
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Peripheral vein
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Cell Type
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B-Lymphocyte
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Tissue Type
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Blood
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Transformant
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Epstein-Barr Virus
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Sample Source
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LCL from B-Lymphocyte
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Species
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Homo sapiens
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Common Name
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Human
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| IDENTIFICATION OF SPECIES OF ORIGIN |
Species of Origin Confirmed by Nucleoside Phosphorylase,Glucose-6-Phosphate Dehydrogenase, and Lactate Dehydrogenase Isoenzyme Electrophoresis |
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| Pharmacogenomics Panel |
For pharmacogenetic variants please click here: GeT-RM PGx Search |
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| Gene |
HLA-B |
| Chromosomal Location |
6p21.3 |
| Allelic Variant 1 |
142830.0002; STEVENS-JOHNSON SYNDROME, SUSCEPTIBILITY TO |
| Identified Mutation |
HLA-B*1502 |
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| Gene |
HLA-B |
| Chromosomal Location |
6p21.3 |
| Allelic Variant 2 |
; |
| Identified Mutation |
HLA-B*1511 |
| Genbank |
Hypervariable region I |
| Wang X, Abudu A, Son S, Dang Y, Venta PJ, Zheng YH, Analysis of Human APOBEC3H Haplotypes and Anti-Human Immunodeficiency Virus Type-1 Activity Journal of virology85(7):3142-52 2011 |
| PubMed ID: 21270145 |
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| Pratt VM, Zehnbauer B, Wilson JA, Baak R, Babic N, Bettinotti M, Buller A, Butz K, Campbell M, Civalier C, El-Badry A, Farkas DH, Lyon E, Mandal S, McKinney J, Muralidharan K, Noll L, Sander T, Shabbeer J, Smith C, Telatar M, Toji L, Vairavan A, Vance C, Weck KE, Wu AH, Yeo KT, Zeller M, and Kalman L., Characterization of 107 Genomic DNA Reference Materials for CYP2D6, CYP2C19, CYP2C9, VKORC1, and UGT1A1 J Mol Diagn12(6):835-46 2010 |
| PubMed ID: 20889555 |
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| Anderle P, Nielsen CU, Pinsonneault J, Krog PL, Brodin B, Sadée W, Genetic variants of the human dipeptide transporter PEPT1 The Journal of pharmacology and experimental therapeutics316:636-46 2005 |
| PubMed ID: 16258023 |
| Split Ratio |
1:3 |
| Temperature |
37 C |
| Percent CO2 |
5% |
| Percent O2 |
AMBIENT |
| Medium |
Roswell Park Memorial Institute Medium 1640 with 2mM L-glutamine or equivalent |
| Serum |
15% fetal bovine serum Not Inactivated |
| Substrate |
None specified |
| Subcultivation Method |
dilution - add fresh medium |
| Supplement |
- |
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