GM05912
LCL from B-Lymphocyte
Description:
WILMS TUMOR 1; WT1
INVERTED CHROMOSOME
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Repository
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NIGMS Human Genetic Cell Repository
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| Subcollection |
Chromosome Abnormalities
Heritable Diseases |
| Class |
Heritable Cancer Syndromes and other Cancers |
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Biopsy Source
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Peripheral vein
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Cell Type
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B-Lymphocyte
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Tissue Type
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Blood
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Transformant
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Epstein-Barr Virus
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Sample Source
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LCL from B-Lymphocyte
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Race
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White
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Family Member
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1
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Relation to Proband
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parent
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Confirmation
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Clinical summary/Case history
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ISCN
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46,XX,ins(11)(pter>p14::p11.2>q22:: p14>p11.2::q22>qter)
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Species
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Homo sapiens
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Common Name
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Human
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Remarks
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| IDENTIFICATION OF SPECIES OF ORIGIN |
Species of Origin Confirmed by Chromosome Analysis |
| |
| Remarks |
Balanced carrier; 46,XX, inv ins(11) (pter>p14::p11.2>q22::p14>p11.2::q22> qter); a daughter had aniridia, multiple anomalies, failure to thrive, & severe psychomotor retardation; affected daughter is not in the Repository |
| de Martinville B, Francke U, The c-Ha-ras1, insulin and beta-globin loci map outside the deletion associated with aniridia-Wilms' tumour. Nature305:641-3 1983 |
| PubMed ID: 6312329 |
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| Strobel RJ, Riccardi VM, Ledbetter DH, Hittner HM, Duplication 11p11.3 leads to 14.1 to meiotic crossing--over. Am J Med Genet7:15-20 1980 |
| PubMed ID: 7211949 |
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| Hittner HM, Riccardi VM, Francke U, Aniridia caused by a heritable chromosome 11 deletion. Ophthalmology86:1173-83 1979 |
| PubMed ID: 230439 |
| Split Ratio |
1:5 |
| Temperature |
37 C |
| Percent CO2 |
5% |
| Medium |
Roswell Park Memorial Institute Medium 1640 with 2mM L-glutamine or equivalent |
| Serum |
15% fetal bovine serum Not Inactivated |
| Substrate |
None specified |
| Subcultivation Method |
dilution - add fresh medium |
| Supplement |
- |
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