June 2025

06/2025

Complete telomere-to telomere genome sequencing of six ape species representing all of the main ape lineages was e-published in the journal Nature last April (https://pubmed.ncbi.nlm.nih.gov/39131277/). Through a major collaborative effort, the authors used these assemblies to characterize a host of common as well as species-specific genomic characteristics, including new genes, structural variants, and regions of rapid divergence. The open-source data is a valuable resource investigating the evolutionary history of our closest relatives and shedding light on human evolution.

Two of the samples used were obtained from the collection of nonhuman primate cell lines of the NIA Aging Cell Repository: AG18354, chimpanzee (pan troglodytes) and AG06209, Sumatran organgutan (pongo pygmaeus).


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