Genome-wide Association Study Identifies Multiple Susceptibility Loci for Glioma


Led by scientists at the Institute of Cancer Research in London, an international team of investigators completed the largest ever study of DNA derived from individuals affected with glioma; the most common form of brain cancer.

Utilizing 1000 Genomes data as a reference, researchers discovered 5 previously unknown variants associated with the disease. Scientists conducted a meta-analysis of 4,167 affected and 7,435 control individuals and used imputation to identify these variants.

Utilization of 1000 Genomes data proved a cost effective means to conduct this type of research on such a large set of genetic variants. 

Additional information on this study can be found in Nature or here on Science Daily.

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