ND07997

Overview

Repository

NINDS Repository

Subcollection

Motor Neuron Disease

Quantity

3 µg

Quantitation Method

Please see our FAQ

Biopsy Source

Peripheral vein

Sample Source

DNA from Whole Blood

Race

White

Subject Type

discordant sib pair

Family Type

NUCLEAR FAMILIES - ONE AFFECTED

Ethnicity

Not Hispanic/Latino

Country of Origin

USA

Family Member

Family History

Relation to Proband

sister

Species

Homo sapiens

Common Name

Human

Note

This material represents a finite resource (DNA from Whole Blood)

Phenotypic Data

Demographic Data

Relation to Proband

sister

Age at Sampling

56 YR

Sex

Female

Age of Onset(If not a control)

No Data

Age at Diagnosis(If not a control)

No Data

Hispanic or Latino/Not Hispanic or Latino

Not Hispanic/Latino

Racial Category

White

Country

USA

Diagnosed By

No Data

Data Elements

Clinical Element Type: Motor Neuron Disorders

(Baseline)

Longitudinal Data

Is this data Longitudinal (Follow-Up) Data?

yes no

Family History

ALS/other MND

present absent unknown
Notes: BROTHER ONLY

Parkinson's disease

present absent unknown

Alzheimer's disease

present absent unknown
Notes: MOM

Other dementia

present absent unknown

Other neurodegenerative disease

present absent unknown

Medical History

Alzheimer's disease

present absent

Ataxia

present absent

Autism

present absent

Bipolar (manic-depressive)

present absent

Brain aneurysm

present absent

Cancer

present absent

Dementia

Alzheimer's
Dementia
absent

Depression

present absent

Diabetes

present absent

Dystonia

present absent

Epilepsy

present absent

Heart disease

present absent

Hypertension

present absent

Multiple sclerosis

present absent

Muscle disease

present absent

Parkinson's

present absent

Schizophrenia

present absent

Suicide/Attempt

present absent

Stroke

present absent

Primary Clinical Diagnosis

Primary clinical diagnosis

Unaffected primary blood relative of proband
Notes: GENETICALLY RELATED TO AFFECTED INDIVIDUAL

Secondary Neurological Diagnosis

Secondary neurological diagnoses

Frontotemporal dementia
Other (specify)
Not Applicable

Site of Symptom Onset

site of symptom onset

No Data

Treatment

Current treatment

Riluzole
PEG
NIPPV
Tracheotomy
Assisted Ventilation > 23 hours
Other (specify)
No Treatment

Signs Supporting Diagnosis

Upper Motor Neuron Signs-Bulbar