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ND20046 DNA from LCL

Description:

ASYMPTOMATIC OR UNDIAGNOSED AND GENETICALLY RELATED TO AN AFFECTED INDIVIDUAL

Affected:

At Risk

Sex:

Male

Age:

44 YR (At Sampling)

  • Overview
  • Phenotypic Data

Overview

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Repository NINDS Repository
Subcollection Tourette Syndrome
Quantity 3 µg
Quantitation Method Please see our FAQ
Biopsy Source Peripheral vein
Cell Type B-Lymphocyte
Tissue Type Blood
Transformant Epstein-Barr Virus
Sample Source LCL from B-Lymphocyte
Race White
Subject Type family with at least 3 members, including 1 proband, not a trio
Family Type NUCLEAR FAMILIES - ONE AFFECTED
Ethnicity Not Hispanic/Latino
Country of Origin USA
Family Member 2
Family History Y
Relation to Proband father
Species Homo sapiens
Common Name Human

Phenotypic Data

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Demographic Data
Relation to Proband father
Age at Sampling 44 YR
Sex Male
Age of Onset(If not a control) No Data
Age at Diagnosis(If not a control) No Data
Hispanic or Latino/Not Hispanic or Latino Not Hispanic/Latino
Racial Category White
Country USA
Diagnosed By No Data
 
Data Elements
Clinical Element Type: Tourettes
  (Baseline)
Primary Lifetime Clinical Diagnosis
Tourette’s Disorder present  absent  
Chronic Multiple Tics present  absent  
Other Tic disorder present  absent  
Unaffected or undiagnosed primary blood relative of proband yes   no 
Symptoms: Motor Tics present  absent  
Symptoms: Vocal/Verbal Tics present  absent  
Age at Tic onset  No Data
Genetic Data of Subject
Mutation/s in subject's DNA (if present, describe) present  absent  unknown  
Secondary Lifetime Clinical Diagnosis
Obsessive compulsive disorder present  absent  
Attention Deficit/Hyperactivity Disorder present  absent  
Other (specify) present  absent  
Optional data
Handedness Right   Left  Ambidextrous 
smoking history never  former smoker   current smoker 
years smoking  5.5
Other family members
Other family members of this person in NINDS repository yes   no 
Notes: SON (PROBAND): ND20045; WIFE: ND20047; SON: ND20048
Family History of TS and related disorders in first degree relatives of subject
Tourette Syndrome or tic disorders present   absent 
Notes: SON (PROBAND): ND20045 HAS TS
Obsessive Compulsive Disorder (OCD) present  absent  
Attention Deficit Hyperactivity Disorder (ADHD) present   absent 
Notes: SON (PROBAND): ND20045 HAS TS, NEPHEW WITH POSSIBLE UNDIAGNOSED ADHD
List all first degree relatives and diagnosis (TS, tic disorder, OCD, ADHD)  SON (PROBAND): ND20045 HAS ADHD DX AND ADHD
Family History of Neurological Disease in first degree relatives
Motor Neuron Disorders, including ALS present  absent  
Parkinson’s disease present  absent  
Epilepsy present  absent  
Cerebrovascular Disorders, including stroke and aneurysm present  absent  
Notes: UNCLE HAD STROKE AT AGE 75

Culture Protocols

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Split Ratio (Frequency) 1:3 (4 Days)
Temperature 37 C
Percent CO2 5%
Percent O2 AMBIENT
Medium Roswell Park Memorial Institute Medium 1640 with 2mM L-glutamine or equivalent
Serum 15% fetal bovine serum Not Inactivated
Substrate None specified
Subcultivation Method dilution - add fresh medium
Supplement -
Pricing
Commercial and Non-U.S.:
$0.00USD
U.S. Academic or
Non-profit:
$0.00USD
NINDS Repository Submitter (past or current) and/or Current NINDS Grantee
$0.00USD
Add to Cart
How to Order
  • Ordering Instructions
  • MTA / Assurance Form
  • Statement of Research Intent Form
Related Products
Same Subject
  • ND20046 - B-Lymphocyte
Same Family
  • NINDS2177

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