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NDPT099 96 WELL PLATE OF DNA SAMPLES

Description: NEUROLOGICALLY NORMAL WHITE CONTROL PANEL

Aliquot Size: 5 µg each

Sex: Males: 46 Females: 46

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Brief Description: This panel contains 5 micrograms of DNA from 92 unique and unrelated White individuals from North America without neurological disorders. Of these, 46 are males and 46 are females, with age at collection ranging from 56-95 years. Data collected on these subjects consisted of Control Clinical Data Elements as outlined in the Coriell NINDS Genetics Repository guidelines. These data include a detailed medical and family history. None have a history of neurological illness in themselves, nor a first degree relative with a known primary neurological disorder. A more detailed description is also available. NDPT099 replaces NDPT024 and has the same samples except ND10976 (same as ND08955 on NDPT098, formerly NPDT022) and ND09875 (not available at present) are removed, and are replaced by ND12315 and ND13844.
Clinical Data: An Excel file with all clinical data is available for download.
Plate Layout: The specific position on the plates has been randomized to reduce any possibility of systematic errors during the genotyping process.
Estrada K, Whelan CW, Zhao F, Bronson P, Handsaker RE, Sun C, Carulli JP, Harris T, Ransohoff RM, McCarroll SA, Day-Williams AG, Greenberg BM, MacArthur DG, A whole-genome sequence study identifies genetic risk factors for neuromyelitis optica Nature communications9:1929 2018
PubMed ID: 29769526
 
Jenkinson EM, Rodero MP, Kasher PR, Uggenti C, Oojageer A, Goosey LC, Rose Y, Kershaw CJ, Urquhart JE, Williams SG, Bhaskar SS, O'Sullivan J, Baerlocher GM, Haubitz M, Aubert G, Barañano KW, Barnicoat AJ, Battini R, Berger A, Blair EM, Brunstrom-Hernandez JE, Buckard JA, Cassiman DM, Caumes R, Cordelli DM, De Waele LM, Fay AJ, Ferreira P, Fletcher NA, Fryer AE, Goel H, Hemingway CA, Henneke M, Hughes I, Jefferson RJ, Kumar R, Lagae L, Landrieu PG, Lourenço CM, Malpas TJ, Mehta SG, Metz I, Naidu S, Õunap K, Panzer A, Prabhakar P, Quaghebeur G, Schiffmann R, Sherr EH, Sinnathuray KR, Soh C, Stewart HS, Stone J, Van Esch H, Van Mol CE, Vanderver A, Wakeling EL, Whitney A, Pavitt GD, Griffiths-Jones S, Rice GI, Revy P, van der Knaap MS, Livingston JH, O'Keefe RT, Crow YJ, Mutations in SNORD118 cause the cerebral microangiopathy leukoencephalopathy with calcifications and cysts Nature genetics48:1185-92 2015
PubMed ID: 27571260
 
Li QS, Cheng P, Favis R, Wickenden A, Romano G, Wang H, SCN9A Variants may be Implicated in Neuropathic Pain Associated with Diabetic Peripheral Neuropathy and Pain Severity The Clinical journal of pain48:1185-92 2015
PubMed ID: 25585270
 
Ferrari R, Mok K, Moreno JH, Cosentino S, Goldman J, Pietrini P, Mayeux R, Tierney MC, Kapogiannis D, Jicha GA, Murrell JR, Ghetti B, Wassermann EM, Grafman J, Hardy J, Huey ED, Momeni P, Screening for C9ORF72 repeat expansion in FTLD Neurobiology of aging33:1850.e1-11 2012
PubMed ID: 22459598
 
Ferrari R, Moreno JH, Minhajuddin AT, O'Bryant SE, Reisch JS, Barber RC, Momeni P, Implication of common and disease specific variants in CLU, CR1, and PICALM Neurobiology of aging33:1846.e7-18 2011
PubMed ID: 22402018
 
Lee T, Li YR, Chesi A, Hart MP, Ramos D, Jethava N, Hosangadi D, Epstein J, Hodges B, Bonini NM, Gitler AD, Evaluating the prevalence of polyglutamine repeat expansions in amyotrophic lateral sclerosis Neurology76:2062-5 2011
PubMed ID: 21562248
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Catalog IDSexAge at SamplingFamilyRelationshipGeneMutationAffected
ND10581Male60 YRNINDS1835control family  No
ND10817Male61 YRNINDS1797control family  No
ND10852Female59 YRNINDS1265spouse  No
ND12315Male77 YRNINDS1119spouse  No
ND10727Female56 YRNINDS1047spouse  No
ND10811Female63 YRNINDS1042spouse  No
ND10843Male71 YRNINDS1039spouse  No
ND10487Male70 YRNINDS0908spouse  No
ND10775Female61 YRNINDS0900spouse  No
ND09598Female80 YRNINDS0890spouse  No
ND09887Female62 YRNINDS0862spouse  No
ND09737Male69 YRNINDS0859spouse  No
ND09351Female60 YRNINDS0855spouse  No
ND09717Male63 YRNINDS0845spouse  No
ND09409Female59 YRNINDS0836spouse  No
ND09374Female59 YRNINDS0812spouse  No
ND08981Male78 YRNINDS0802spouse  No
ND08002Male72 YRNINDS0745spouse  No
ND06859Male83 YRNINDS0709spouse  No
ND06395Female68 YRNINDS0597spouse  No
ND05995Male70 YRNINDS0575spouse  No
ND05977Male60 YRNINDS0574spouse  No
ND05253Female71 YRNINDS0517spouse  No
ND04376Female64 YRNINDS0459spouse  No
ND04233Female60 YRNINDS0453spouse  No
ND02961Female82 YRNINDS0330spouseLRRK2WILDTYPE for GLY2019 (Bi)No
ND02820Male84 YRNINDS0318spouse  No
ND01584Male=>90 YRNINDS0167spouse  No
ND01372Male56 YRNINDS0137son-in-law  No
ND01658Female89 YR    No
ND01669Female86 YR    No
ND03969Female83 YR    No
ND01698Female80 YR    No
ND07424Female80 YR    No
ND06348Female77 YR    No
ND08060Female76 YR    No
ND08977Female73 YR    No
ND05280Female72 YR    No
ND04203Female70 YR    No
ND10231Female70 YR    No
ND07553Female68 YR    No
ND05897Female66 YR    No
ND05208Female65 YR    No
ND09433Female65 YR    No
ND10777Female64 YR    No
ND05281Female63 YR    No
ND06762Female63 YR    No
ND04792Female62 YR    No
ND05618Female62 YR    No
ND07549Female61 YR    No
ND10862Female60 YR    No
ND09950Female59 YR    No
ND10882Female59 YR    No
ND13844Female59 YR    No
ND09691Female58 YR    No
ND09768Female58 YR    No
ND05207Female56 YR    No
ND07951Female56 YR    No
ND08277Female56 YR    No
ND09522Female56 YR    No
ND10099Female56 YR    No
ND01689Male=>90 YR    No
ND06258Male79 YR    No
ND06233Male77 YR    No
ND07537Male76 YR    No
ND08391Male75 YR    No
ND08999Male74 YR    No
ND05764Male73 YR    No
ND07543Male73 YR    No
ND08350Male71 YR    No
ND06260Male70 YR    No
ND09773Male69 YR    No
ND05679Male68 YR    No
ND07550Male68 YR    No
ND08393Male67 YR    No
ND06758Male66 YR    No
ND07551Male66 YR    No
ND10365Male64 YR    No
ND06378Male63 YR    No
ND05066Male62 YR    No
ND05685Male61 YR    No
ND06377Male61 YR    No
ND10266Male61 YR    No
ND05279Male60 YR    No
ND06021Male60 YR    No
ND07552Male60 YR    No
ND10040Male60 YR    No
ND04014Male57 YR    No
ND10861Male57 YR    No
ND10879Male57 YR    No
ND06143Male56 YR    No
ND07548Male56 YR    No

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