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NDPT095 96 WELL PLATE OF DNA SAMPLES

Description: NEUROLOGICALLY NORMAL WHITE CONTROL PANEL

Aliquot Size: 5 µg each

Sex: Males: 46 Females: 48

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Brief Description: This panel contains 5 micrograms of DNA from 94 unique and unrelated White non-Hispanic individuals from North America without neurological disorders. Of these, 46 are males and 48 are females, with an age at collection ranging from 58 through =>90 years. Data collected on these subjects consisted of Control Clinical Data Elements as outlined in the Coriell NINDS Genetics Repository guidelines. These data include a detailed medical and family history. None have a history of neurological illness in themselves, nor a first degree relative with a known primary neurological disorder. A more detailed description is also available. As an internal control, ND09230 appears twice on the panel, in F08 and well H12. Well C02 is empty for addition of a laboratory control.
Plate Layout: The specific position on the plates has been randomized to reduce any possibility of systematic errors during the genotyping process.
Estrada K, Whelan CW, Zhao F, Bronson P, Handsaker RE, Sun C, Carulli JP, Harris T, Ransohoff RM, McCarroll SA, Day-Williams AG, Greenberg BM, MacArthur DG, A whole-genome sequence study identifies genetic risk factors for neuromyelitis optica Nature communications9:1929 2018
PubMed ID: 29769526
 
Jenkinson EM, Rodero MP, Kasher PR, Uggenti C, Oojageer A, Goosey LC, Rose Y, Kershaw CJ, Urquhart JE, Williams SG, Bhaskar SS, O'Sullivan J, Baerlocher GM, Haubitz M, Aubert G, Barañano KW, Barnicoat AJ, Battini R, Berger A, Blair EM, Brunstrom-Hernandez JE, Buckard JA, Cassiman DM, Caumes R, Cordelli DM, De Waele LM, Fay AJ, Ferreira P, Fletcher NA, Fryer AE, Goel H, Hemingway CA, Henneke M, Hughes I, Jefferson RJ, Kumar R, Lagae L, Landrieu PG, Lourenço CM, Malpas TJ, Mehta SG, Metz I, Naidu S, Õunap K, Panzer A, Prabhakar P, Quaghebeur G, Schiffmann R, Sherr EH, Sinnathuray KR, Soh C, Stewart HS, Stone J, Van Esch H, Van Mol CE, Vanderver A, Wakeling EL, Whitney A, Pavitt GD, Griffiths-Jones S, Rice GI, Revy P, van der Knaap MS, Livingston JH, O'Keefe RT, Crow YJ, Mutations in SNORD118 cause the cerebral microangiopathy leukoencephalopathy with calcifications and cysts Nature genetics48:1185-92 2015
PubMed ID: 27571260
 
Li QS, Cheng P, Favis R, Wickenden A, Romano G, Wang H, SCN9A Variants may be Implicated in Neuropathic Pain Associated with Diabetic Peripheral Neuropathy and Pain Severity The Clinical journal of pain48:1185-92 2015
PubMed ID: 25585270
 
Lee T, Li YR, Chesi A, Hart MP, Ramos D, Jethava N, Hosangadi D, Epstein J, Hodges B, Bonini NM, Gitler AD, Evaluating the prevalence of polyglutamine repeat expansions in amyotrophic lateral sclerosis Neurology76:2062-5 2011
PubMed ID: 21562248
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Catalog IDSexAge at SamplingFamilyRelationshipGeneMutationAffected
ND11151Male68 YRNINDS1552spouse  No
ND14071Female59 YRNINDS1524unaffected spouse  No
ND13701Female59 YRNINDS1501spouse  No
ND11289Female62 YRNINDS1468spouse  No
ND10834Female69 YRNINDS1375unaffected spouse  No
ND14309Female58 YRNINDS1371spouse  No
ND13891Male58 YRNINDS1314unaffected spouse  No
ND11322Male73 YRNINDS1238spouse  No
ND11144Female62 YRNINDS1233unaffected spouse  No
ND10611Male68 YRNINDS1231unaffected spouse  No
ND10602Female60 YRNINDS1229unaffected spouse  No
ND10596Female58 YRNINDS1226unaffected spouse  No
ND10594Male68 YRNINDS1223unaffected spouse  No
ND10593Male60 YRNINDS1222unaffected spouse  No
ND09879Female71 YRNINDS1205spouse  No
ND10592Male75 YRNINDS1204unaffected spouse  No
ND11442Female74 YRNINDS1139spouse  No
ND12127Female58 YRNINDS1099unaffected spouse  No
ND11373Female72 YRNINDS1073spouse  No
ND11105Female62 YRNINDS1032spouse  No
ND11518Male59 YRNINDS1006unaffected spouse  No
ND11409Male63 YRNINDS1004unaffected spouse  No
ND10750Female77 YRNINDS0922spouse  No
ND10420Female68 YRNINDS0879spouse  No
ND10259Male67 YRNINDS0877spouse  No
ND09676Male62 YRNINDS0873spouse  No
ND09488Male66 YRNINDS0837spouse  No
ND09230Male73 YRNINDS0831spouse  No
ND08467Male79 YRNINDS0761spouse  No
ND07730Female70 YRNINDS0742aunt-in-law  No
ND07723Male72 YRNINDS0742uncle-in-law  No
ND07728Male62 YRNINDS0742uncle-in-law  No
ND06450Female68 YRNINDS0600spouse  No
ND06294Female63 YRNINDS0586spouse  No
ND02715Female63 YRNINDS0289spouseLRRK2WILDTYPE for GLY2019 (Bi)No
ND02528Female61 YRNINDS0258spouseLRRK2WILDTYPE for GLY2019 (Bi)No
ND02299Female81 YRNINDS0239spouseLRRK2WILDTYPE for GLY2019 (Bi)No
ND01667Male81 YRNINDS0163spouse  No
ND01760Female65 YRNINDS0159spouseLRRK2WILDTYPE for GLY2019 (Bi)No
ND01399Female68 YRNINDS0138spouse  No
ND01550Female=>90 YR    No
ND01696Female85 YR    No
ND06868Female83 YR    No
ND05212Female81 YR    No
ND08674Female79 YR    No
ND08447Female78 YR    No
ND07334Female77 YR    No
ND08030Female77 YR    No
ND07015Female74 YR    No
ND08287Female74 YR    No
ND04583Female71 YR    No
ND09779Female69 YR    No
ND10858Female69 YR    No
ND11058Female68 YR    No
ND01336Female65 YR    No
ND08958Female65 YR    No
ND11264Female65 YR    No
ND10603Female64 YR    No
ND11067Female63 YR    No
ND07186Female62 YR    No
ND10233Female62 YR    No
ND11107Female61 YR    No
ND11263Female61 YR    No
ND11383Female61 YR    No
ND08368Female59 YR    No
ND05767Male75 YR    No
ND08286Male75 YR    No
ND02155Male73 YR    No
ND02432Male73 YR  LRRK2WILDTYPE for GLY2019 (Bi)No
ND10868Male73 YR    No
ND01782Male72 YR    No
ND05028Male72 YR    No
ND06358Male72 YR    No
ND10020Male72 YR    No
ND11502Male71 YR    No
ND10683Male70 YR    No
ND06229Male69 YR    No
ND08721Male68 YR spouse  No
ND11052Male67 YR    No
ND11500Male67 YR    No
ND07949Male66 YR    No
ND10604Male66 YR    No
ND11415Male66 YR    No
ND06382Male64 YR    No
ND08029Male64 YR    No
ND09465Male63 YR    No
ND10227Male63 YR    No
ND10857Male62 YR    No
ND06080Male61 YR    No
ND06346Male61 YR    No
ND06792Male61 YR    No
ND08027Male61 YR    No
ND06261Male60 YR    No
ND13185Male59 YR    No

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