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NDPT090 96 WELL PLATE OF DNA SAMPLES

Description: NEUROLOGICALLY NORMAL WHITE CONTROL PANEL

Aliquot Size: 5 µg each

Sex: Males: 32 Females: 59

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Brief Description: This panel contains 5 micrograms of DNA from 91 unique and unrelated White individuals from North America without neurological disorders. Of these, 32 are males and 59 are females, with an age at collection ranging from 19-38 years. Data collected on these subjects consisted of Control Clinical Data Elements as outlined in the Coriell NINDS Genetics Repository guidelines. These data include a detailed medical and family history. None have a history of neurological illness in themselves, nor a first degree relative with a known primary neurological disorder. A more detailed description is also available. NDPT090 replaces NDPT019 and has the same samples except the following samples have been removed: ND08964, ND09780, ND10058, ND10280, ND10481, ND10495, ND10867, ND08986, ND10343, ND09727, ND02433, ND09305, ND09893, ND10299, ND08500, ND08501, and ND9964. These have been replaced with: ND11622, ND12953, ND01057, ND10601, ND11061, ND12595, ND13305, ND13333, ND14032, ND14128, ND14298, ND14003, ND11191, ND14519, ND12146, and ND11298. As an internal control, ND14003 appears twice on the panel, in B01 and well D11.
Clinical Data: An Excel file with all clinical data is available for download.
Plate Layout: The specific position on the plates has been optimized to reduce any possible errors in sample identity during the genotyping process.
Estrada K, Whelan CW, Zhao F, Bronson P, Handsaker RE, Sun C, Carulli JP, Harris T, Ransohoff RM, McCarroll SA, Day-Williams AG, Greenberg BM, MacArthur DG, A whole-genome sequence study identifies genetic risk factors for neuromyelitis optica Nature communications9:1929 2018
PubMed ID: 29769526
 
Phelps IG, Dempsey JC, Grout ME, Isabella CR, Tully HM, Doherty D, Bachmann-Gagescu R, Interpreting the clinical significance of combined variants in multiple recessive disease genes: systematic investigation of Joubert syndrome yields little support for oligogenicity Genetics in medicine : official journal of the American College of Medical Genetics9:1929 2017
PubMed ID: 28771248
 
Slaats GG, Isabella CR, Kroes HY, Dempsey JC, Gremmels H, Monroe GR, Phelps IG, Duran KJ, Adkins J, Kumar SA, Knutzen DM, Knoers NV, Mendelsohn NJ, Neubauer D, Mastroyianni SD, Vogt J, Worgan L, Karp N, Bowdin S, Glass IA, Parisi MA, Otto EA, Johnson CA, Hildebrandt F, van Haaften G, Giles RH, Doherty D, MKS1 regulates ciliary INPP5E levels in Joubert syndrome Journal of medical genetics53:62-72 2015
PubMed ID: 26490104
 
Vester A, Velez-Ruiz G, McLaughlin HM, NISC Comparative Sequencing Program HM, Lupski JR, Talbot K, Vance JM, Züchner S, Roda RH, Fischbeck KH, Biesecker LG, Nicholson G, Beg AA, Antonellis A, A loss-of-function variant in the human histidyl-tRNA synthetase (HARS) gene is neurotoxic in vivo Human mutation34:191-9 2012
PubMed ID: 22930593
 
Lee T, Li YR, Chesi A, Hart MP, Ramos D, Jethava N, Hosangadi D, Epstein J, Hodges B, Bonini NM, Gitler AD, Evaluating the prevalence of polyglutamine repeat expansions in amyotrophic lateral sclerosis Neurology76:2062-5 2011
PubMed ID: 21562248
How to Order
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Catalog IDSexAge at SamplingFamilyRelationshipAffected
ND11622Male35 YRNINDS1138spouseNo
ND08538Female34 YRNINDS0760nieceNo
ND06393Female33 YRNINDS0596spouseNo
ND14519Female38 YR  No
ND10838Female35 YR  No
ND10981Female35 YR  No
ND05521Female34 YR  No
ND09425Female34 YR  No
ND09962Female34 YR  No
ND10636Female34 YR  No
ND10872Female34 YR  No
ND10880Female34 YR  No
ND04280Female33 YR  No
ND04338Female33 YR  No
ND05169Female33 YR  No
ND10009Female33 YR  No
ND05805Female32 YR  No
ND10462Female32 YR  No
ND10530Female32 YR  No
ND04542Female31 YR  No
ND09612Female31 YR  No
ND09985Female31 YR  No
ND04068Female30 YR  No
ND09330Female30 YR  No
ND10332Female30 YR  No
ND09659Female29 YR  No
ND10268Female29 YR  No
ND10954Female29 YR  No
ND04310Female28 YR  No
ND09778Female28 YR  No
ND10587Female28 YR  No
ND10952Female28 YR  No
ND10960Female28 YR  No
ND09324Female27 YR  No
ND10417Female27 YR  No
ND04239Female26 YR  No
ND09150Female26 YR  No
ND09151Female26 YR  No
ND09422Female26 YR  No
ND09594Female26 YR  No
ND09650Female26 YR  No
ND10057Female26 YR  No
ND10694Female26 YR  No
ND08230Female25 YR  No
ND09649Female25 YR  No
ND10345Female25 YR  No
ND04336Female24 YR  No
ND04382Female24 YR  No
ND09891Female24 YR  No
ND10107Female24 YR  No
ND10955Female24 YR  No
ND05232Female23 YR  No
ND09152Female23 YR  No
ND09457Female23 YR  No
ND10012Female23 YR  No
ND10349Female22 YR  No
ND09730Female20 YR  No
ND10957Female20 YR  No
ND04279Female19 YR  No
ND09729Female19 YR  No
ND11191Male38 YR  No
ND01057Male36 YR  No
ND10601Male36 YR  No
ND11061Male36 YR  No
ND12595Male36 YR  No
ND13305Male36 YR  No
ND13333Male36 YR  No
ND14032Male36 YR  No
ND14128Male36 YR  No
ND14298Male36 YR  No
ND12953Male35 YR  No
ND04284Male34 YR  No
ND08767Male34 YR  No
ND09961Male34 YR  No
ND10447Male34 YR  No
ND10910Male34 YR  No
ND14003Male34 YR  No
ND01843Male33 YR  No
ND05166Male33 YR  No
ND04673Male32 YR  No
ND09739Male32 YR  No
ND09660Male31 YR  No
ND12146Male30 YR  No
ND00484Male28 YR  No
ND10815Male28 YR  No
ND04188Male27 YR  No
ND03635Male26 YR  No
ND07031Male25 YR  No
ND10580Male25 YR  No
ND11298Male25 YR  No
ND08985Male24 YR  No

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