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NDPT087 96 WELL PLATE OF DNA SAMPLES

Description: YOUNG ONSET PARKINSON'S PANEL: AFFECTED INDIVIDUALS

Aliquot Size: 5 µg each

Sex: Males: 51 Females: 39

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Brief Description: This panel contains 5 micrograms of DNA from 90 unique and unrelated White individuals with young onset Parkinson's disease (YOPD). These include 51 males and 39 females from North America. The age of PD onset ranges from 7 years to 40 years. All subjects meet the UK Brain Bank Criteria for idiopathic Parkinson's disease [Hughes et al. JNNP 55:181-184 (1992)]. None have apparent Mendelian inheritance of PD. A more detailed description is also available. NDPT087 replaces NPDT014 and it has all of the same samples, except: ND00887 was removed because it is from the same subject as ND02272 (present on this panel), ND00072 was removed because it was discovered to have a known mutation in LRRK2 (IVS20+4DELGT), and ND09440 replaces ND04741.
Plate Layout: The specific position on the plates has been optimized to reduce any possible errors in sample identity during the genotyping process.
van Bree EJ, Guimarães RLFP, Lundberg M, Blujdea ER, Rosenkrantz JL, White FTG, Poppinga J, Ferrer-Raventós P, Schneider AE, Clayton I, Haussler D, Reinders MJT, Holstege H, Ewing AD, Moses C, Jacobs FMJ, A hidden layer of structural variation in transposable elements reveals potential genetic modifiers in human disease-risk loci Genome research32:656-670 2021
PubMed ID: 35332097
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Catalog IDSexAge at SamplingFamilyRelationshipGeneMutationAffected
ND00064Male38 YRNINDS1587proband  Yes
ND06502Female41 YRNINDS0603proband  Yes
ND06392Male40 YRNINDS0596proband  Yes
ND06246Male35 YRNINDS0591proband  Yes
ND05705Female36 YRNINDS0563proband  Yes
ND05122Male41 YRNINDS0521proband  Yes
ND03375Male46 YRNINDS0367proband  Yes
ND02798Female66 YRNINDS0313probandLRRK2WILDTYPE for GLY2019 (Bi)Yes
ND02755Male61 YRNINDS0310probandLRRK2WILDTYPE for GLY2019 (Bi)Yes
ND02710Male57 YRNINDS0292probandLRRK2WILDTYPE for GLY2019 (Bi)Yes
ND02644Male69 YRNINDS0280probandLRRK2WILDTYPE for GLY2019 (Bi)Yes
ND02639Male69 YRNINDS0278probandLRRK2WILDTYPE for GLY2019 (Bi)Yes
ND02263Female59 YRNINDS0235probandLRRK2WILDTYPE for GLY2019 (Bi)Yes
ND01883Male54 YRNINDS0207proband  Yes
ND00143Male30 YRNINDS0168proband  Yes
ND00816Male56 YRNINDS0094proband  Yes
ND00363Female44 YRNINDS0080probandLRRK2WILDTYPE for GLY2019 (Bi)Yes
ND00415Male53 YRNINDS0048probandLRRK2WILDTYPE for GLY2019 (Bi)Yes
ND00386Female48 YRNINDS0042probandLRRK2WILDTYPE for GLY2019 (Bi)Yes
ND00355Male54 YRNINDS0040probandLRRK2WILDTYPE for GLY2019 (Bi)Yes
ND00187Female54 YRNINDS0037probandLRRK2WILDTYPE for GLY2019 (Bi)Yes
ND00280Male40 YRNINDS0035proband  Yes
ND00308Male53 YRNINDS0033probandLRRK2WILDTYPE for GLY2019 (Bi)Yes
ND00136Female48 YRNINDS0024probandLRRK2WILDTYPE for GLY2019 (Bi)Yes
ND00277Male65 YRNINDS0022probandLRRK2WILDTYPE for GLY2019 (Bi)Yes
ND00447Female46 YRNINDS0019probandLRRK2WILDTYPE for GLY2019 (Bi)Yes
ND00087Female35 YRNINDS0010proband  Yes
ND00007Female34 YRNINDS0004probandLRRK2WILDTYPE for GLY2019 (Bi)Yes
ND00002Female38 YRNINDS0003probandLRRK2WILDTYPE for GLY2019 (Bi)Yes
ND00030Male38 YRNINDS0001probandLRRK2WILDTYPE for GLY2019 (Bi)Yes
ND03769Female77 YR  LRRK2WILDTYPE for GLY2019 (Bi)Yes
ND00417Female64 YR  LRRK2WILDTYPE for GLY2019 (Bi)Yes
ND01120Female63 YR  LRRK2WILDTYPE for GLY2019 (Bi)Yes
ND00154Female59 YR  LRRK2WILDTYPE for GLY2019 (Bi)Yes
ND00128Female58 YR    Yes
ND20374Female58 YR    Yes
ND20355Female57 YR    Yes
ND00428Female53 YR  LRRK2WILDTYPE for GLY2019 (Bi)Yes
ND00544Female50 YR    Yes
ND02757Female50 YR  LRRK2WILDTYPE for GLY2019 (Bi)Yes
ND08193Female49 YR    Yes
ND00129Female48 YR    Yes
ND06966Female48 YR    Yes
ND01755Female47 YR  LRRK2WILDTYPE for GLY2019 (Bi)Yes
ND00033Female46 YR    Yes
ND00548Female46 YR    Yes
ND00058Female44 YR  LRRK2WILDTYPE for GLY2019 (Bi)Yes
ND00134Female44 YR  LRRK2WILDTYPE for GLY2019 (Bi)Yes
ND00393Female44 YR    Yes
ND00021Female43 YR    Yes
ND00132Female43 YR    Yes
ND00071Female40 YR  LRRK2WILDTYPE for GLY2019 (Bi)Yes
ND04026Female40 YR  LRRK2WILDTYPE for GLY2019 (Bi)Yes
ND00390Female39 YR    Yes
ND08875Female36 YR    Yes
ND06296Female35 YR    Yes
ND04581Female22 YR    Yes
ND01573Male83 YR    Yes
ND03003Male60 YR  LRRK2WILDTYPE for GLY2019 (Bi)Yes
ND03593Male58 YR  LRRK2WILDTYPE for GLY2019 (Bi)Yes
ND08723Male58 YR    Yes
ND00409Male57 YR  LRRK2WILDTYPE for GLY2019 (Bi)Yes
ND00081Male56 YR  LRRK2WILDTYPE for GLY2019 (Bi)Yes
ND00149Male56 YR    Yes
ND00547Male56 YR    Yes
ND05259Male54 YR    Yes
ND07202Male53 YR    Yes
ND00124Male52 YR    Yes
ND00155Male52 YR  LRRK2WILDTYPE for GLY2019 (Bi)Yes
ND01085Male52 YR  LRRK2WILDTYPE for GLY2019 (Bi)Yes
ND05498Male52 YR    Yes
ND00265Male51 YR  LRRK2WILDTYPE for GLY2019 (Bi)Yes
ND01425Male50 YR  LRRK2WILDTYPE for GLY2019 (Bi)Yes
ND00004Male49 YR    Yes
ND00153Male49 YR  LRRK2WILDTYPE for GLY2019 (Bi)Yes
ND00313Male48 YR  LRRK2WILDTYPE for GLY2019 (Bi)Yes
ND00549Male46 YR    Yes
ND05973Male45 YR    Yes
ND00127Male44 YR    Yes
ND06164Male44 YR    Yes
ND00010Male42 YR  LRRK2WILDTYPE for GLY2019 (Bi)Yes
ND04149Male39 YR    Yes
ND00039Male38 YR    Yes
ND02578Male38 YR  LRRK2WILDTYPE for GLY2019 (Bi)Yes
ND02272Male36 YR    Yes
ND00023Male35 YR    Yes
ND00088Male34 YR  LRRK2WILDTYPE for GLY2019 (Bi)Yes
ND00006Male32 YR    Yes
ND09440Male31 YR    Yes
ND04985Male29 YR    Yes

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