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NDPT084 96 WELL PLATE OF DNA SAMPLES

Description: NEUROLOGICALLY NORMAL WHITE CONTROL PANEL

Aliquot Size: 5 µg each

Sex: Males: 38 Females: 54

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Brief Description: This panel contains 5 micrograms of DNA from 92 unique and unrelated White individuals from the United States without neurological disorders. Of these, 38 are males and 54 females, with an age range from 55-88 years. Data collected on these subjects consisted of Control Clinical Data Elements as outlined in the Coriell NINDS Genetics Repository guidelines. These data include a detailed medical and family history, and in most cases a neurological examination and Folstein Mini-Mental Status examination score. None have a history of neurological illness in themselves, nor a first degree relative with a known primary neurological disorder. A more detailed description is also available. NDPT084 replaces NDPT002 and has all of the same samples, except: ND11416 replaces ND01096, ND02200 replaces ND01568, and ND10909 replaces ND01708.
Plate Layout: The specific position on the plates has been optimized to reduce any possible errors in sample identity during the genotyping process.
Estrada K, Whelan CW, Zhao F, Bronson P, Handsaker RE, Sun C, Carulli JP, Harris T, Ransohoff RM, McCarroll SA, Day-Williams AG, Greenberg BM, MacArthur DG, A whole-genome sequence study identifies genetic risk factors for neuromyelitis optica Nature communications9:1929 2018
PubMed ID: 29769526
 
Vester A, Velez-Ruiz G, McLaughlin HM, NISC Comparative Sequencing Program HM, Lupski JR, Talbot K, Vance JM, Züchner S, Roda RH, Fischbeck KH, Biesecker LG, Nicholson G, Beg AA, Antonellis A, A loss-of-function variant in the human histidyl-tRNA synthetase (HARS) gene is neurotoxic in vivo Human mutation34:191-9 2012
PubMed ID: 22930593
 
Lee T, Li YR, Chesi A, Hart MP, Ramos D, Jethava N, Hosangadi D, Epstein J, Hodges B, Bonini NM, Gitler AD, Evaluating the prevalence of polyglutamine repeat expansions in amyotrophic lateral sclerosis Neurology76:2062-5 2011
PubMed ID: 21562248
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Catalog IDSexAge at SamplingFamilyRelationshipGeneMutationAffected
ND01880Male70 YRNINDS0412spouseLRRK2WILDTYPE for GLY2019 (Bi)No
ND00723Female64 YRNINDS0283spouse  No
ND02296Female65 YRNINDS0238spouseLRRK2WILDTYPE for GLY2019 (Bi)No
ND02212Female74 YRNINDS0227spouseLRRK2WILDTYPE for GLY2019 (Bi)No
ND01983Male65 YRNINDS0219spouseLRRK2WILDTYPE for GLY2019 (Bi)No
ND01944Male68 YRNINDS0215spouseLRRK2WILDTYPE for GLY2019 (Bi)No
ND01942Male69 YRNINDS0214spouseLRRK2WILDTYPE for GLY2019 (Bi)No
ND01940Female62 YRNINDS0213spouseLRRK2WILDTYPE for GLY2019 (Bi)No
ND01938Male70 YRNINDS0212spouseLRRK2WILDTYPE for GLY2019 (Bi)At Risk
ND01936Male55 YRNINDS0211spouseLRRK2WILDTYPE for GLY2019 (Bi)No
ND01929Male73 YRNINDS0209spouseLRRK2WILDTYPE for GLY2019 (Bi)No
ND01887Female63 YRNINDS0208spouseLRRK2WILDTYPE for GLY2019 (Bi)No
ND01801Female69 YRNINDS0193spouseLRRK2WILDTYPE for GLY2019 (Bi)No
ND01527Female76 YRNINDS0180spouse  No
ND01525Female61 YRNINDS0179spouse  No
ND01528Male59 YRNINDS0178spouse  No
ND01523Female66 YRNINDS0177spouse  No
ND01496Male75 YRNINDS0176spouse  No
ND01569Male75 YRNINDS0165spouse  No
ND01692Female84 YRNINDS0164spouse  No
ND01691Male86 YRNINDS0164spouse  No
ND01840Male60 YRNINDS0162spouse  No
ND01705Male78 YRNINDS0152spouseLRRK2WILDTYPE for GLY2019 (Bi)No
ND01703Female68 YRNINDS0151spouseLRRK2WILDTYPE for GLY2019 (Bi)No
ND01630Female73 YRNINDS0149spouseLRRK2WILDTYPE for GLY2019 (Bi)No
ND01613Female77 YRNINDS0148spouseLRRK2WILDTYPE for GLY2019 (Bi)No
ND01611Male76 YRNINDS0147spouseLRRK2WILDTYPE for GLY2019 (Bi)No
ND01424Female76 YRNINDS0140spouseLRRK2WILDTYPE for GLY2019 (Bi)No
ND01354Male80 YRNINDS0134spouseLRRK2WILDTYPE for GLY2019 (Bi)No
ND01277Female68 YRNINDS0125spouseLRRK2WILDTYPE for GLY2019 (Bi)No
ND01220Male74 YRNINDS0122husbandLRRK2WILDTYPE for GLY2019 (Bi)No
ND01217Female69 YRNINDS0120spouseLRRK2WILDTYPE for GLY2019 (Bi)No
ND01212Female73 YRNINDS0118spouseLRRK2WILDTYPE for GLY2019 (Bi)No
ND01205Female71 YRNINDS0113spouseLRRK2WILDTYPE for GLY2019 (Bi)No
ND00709Female72 YRNINDS0093spouse  No
ND00745Male55 YRNINDS0091spouse  No
ND00714Female58 YRNINDS0082spouse  No
ND00706Female64 YRNINDS0079spouse  No
ND00694Female59 YRNINDS0074spouse  No
ND00689Female56 YRNINDS0072spouse  No
ND00679Male71 YRNINDS0068spouse  At Risk
ND00677Male61 YRNINDS0067son-in-law  No
ND00672Female77 YRNINDS0065spouse  No
ND00665Male62 YRNINDS0061spouse  No
ND00592Female58 YRNINDS0059spouse  No
ND00412Male77 YRNINDS0047spouse  No
ND01099Female79 YRNINDS0020aunt-in-law  No
ND01660Female88 YR    No
ND01671Female88 YR    No
ND01552Female86 YR    No
ND01562Female86 YR    No
ND01682Female86 YR    No
ND01702Female86 YR    No
ND01699Female85 YR    No
ND01577Female84 YR    No
ND01657Female84 YR    No
ND01695Female84 YR    No
ND01567Female83 YR    No
ND01678Female83 YR    No
ND01688Female83 YR  LRRK2WILDTYPE for GLY2019 (Bi)No
ND01700Female83 YR    No
ND01207Female81 YR  LRRK2WILDTYPE for GLY2019 (Bi)No
ND01666Female81 YR    No
ND01690Female81 YR    No
ND01675Female80 YR    No
ND01686Female80 YR    No
ND00707Female78 YR    No
ND01563Female78 YR    No
ND01565Female78 YR    No
ND01659Female76 YR    No
ND01566Female75 YR    No
ND00727Female74 YR    No
ND01934Female59 YR  LRRK2WILDTYPE for GLY2019 (Bi)No
ND11416Female58 YR    No
ND01317Female57 YR  LRRK2WILDTYPE for GLY2019 (Bi)No
ND01670Male88 YR    No
ND01684Male88 YR    No
ND01583Male86 YR    No
ND01701Male85 YR  LRRK2WILDTYPE for GLY2019 (Bi)No
ND01679Male84 YR    No
ND01574Male82 YR    No
ND01674Male80 YR    No
ND02200Male80 YR    No
ND01548Male79 YR    No
ND01588Male79 YR    No
ND01676Male78 YR    No
ND01504Male77 YR spouse  No
ND10909Male77 YR    No
ND01580Male73 YR    No
ND01885Male71 YR spouseLRRK2WILDTYPE for GLY2019 (Bi)No
ND00728Male62 YR    No
ND01757Male57 YR  LRRK2WILDTYPE for GLY2019 (Bi)No

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