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NDPT082 96 WELL PLATE OF DNA SAMPLES

Description: NEUROLOGICALLY NORMAL WHITE CONTROL PANEL

Aliquot Size: 5 µg each

Sex: Males: 27 Females: 65

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Brief Description: This panel contains 5 micrograms of DNA from 92 unique and unrelated White individuals from North America without neurological disorders. Of these, 27 are males and 65 are females, with an age at collection ranging from 46-53 years. Data collected on these subjects consisted of Control Clinical Data Elements as outlined in the Coriell NINDS Genetics Repository guidelines. data include a detailed medical and family history. None have a history of neurological illness in themselves, nor a first degree relative with a known primary neurological disorder. A more detailed description is also available. NDPT082 replaces NDPT021 and it has all of the same samples, except ND08724 replaces ND02927.
Clinical Data: An Excel file with all clinical data is available for download.
Plate Layout: The specific position on the plates has been randomized to reduce any possibility of systematic errors during the genotyping process.
Estrada K, Whelan CW, Zhao F, Bronson P, Handsaker RE, Sun C, Carulli JP, Harris T, Ransohoff RM, McCarroll SA, Day-Williams AG, Greenberg BM, MacArthur DG, A whole-genome sequence study identifies genetic risk factors for neuromyelitis optica Nature communications9:1929 2018
PubMed ID: 29769526
 
Raza MH, Domingues CE, Webster R, Sainz E, Paris E, Rahn R, Gutierrez J, Chow HM, Mundorff J, Kang CS, Riaz N, Basra MA, Khan S, Riazuddin S, Moretti-Ferreira D, Braun A, Drayna D, Mucolipidosis types II and III and non-syndromic stuttering are associated with different variants in the same genes European journal of human genetics : EJHG24:529-34 2015
PubMed ID: 26130485
 
Raza MH, Mattera R, Morell R, Sainz E, Rahn R, Gutierrez J, Paris E, Root J, Solomon B, Brewer C, Basra MA, Khan S, Riazuddin S, Braun A, Bonifacino JS, Drayna D, Association between Rare Variants in AP4E1, a Component of Intracellular Trafficking, and Persistent Stuttering American journal of human genetics97:715-25 2015
PubMed ID: 26544806
 
Vester A, Velez-Ruiz G, McLaughlin HM, NISC Comparative Sequencing Program HM, Lupski JR, Talbot K, Vance JM, Züchner S, Roda RH, Fischbeck KH, Biesecker LG, Nicholson G, Beg AA, Antonellis A, A loss-of-function variant in the human histidyl-tRNA synthetase (HARS) gene is neurotoxic in vivo Human mutation34:191-9 2012
PubMed ID: 22930593
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Catalog IDSexAge at SamplingFamilyRelationshipGeneMutationAffected
ND08851Female49 YRNINDS1161spouse  No
ND09784Male49 YRNINDS1075spouse  No
ND10722Female50 YRNINDS0928spouse  No
ND10119Female52 YRNINDS0917spouse  No
ND10380Male53 YRNINDS0915spouse  No
ND10399Male48 YRNINDS0913spouse  No
ND09989Female46 YRNINDS0899spouse  No
ND09467Male52 YRNINDS0897spouse  No
ND10015Female49 YRNINDS0894spouse  No
ND09608Female47 YRNINDS0893spouse  No
ND09602Male51 YRNINDS0891spouse  No
ND10699Female52 YRNINDS0889spouse  No
ND09716Male49 YRNINDS0858spouse  No
ND09557Male50 YRNINDS0841spouse  No
ND09408Female53 YRNINDS0815spouse  No
ND09287Male53 YRNINDS0806spouse  No
ND09113Female50 YRNINDS0804spouse  No
ND09015Female51 YRNINDS0803spouse  No
ND09135Female50 YRNINDS0792spouse  No
ND08543Male47 YRNINDS0760in-law  No
ND08188Female50 YRNINDS0664spouse  No
ND06680Female49 YRNINDS0618spouse  No
ND05951Female50 YRNINDS0571spouse  No
ND05292Male53 YRNINDS0525spouse  No
ND04071Female47 YRNINDS0441spouse  No
ND04108Female48 YRNINDS0438spouse  No
ND03609Female52 YRNINDS0391spouse  No
ND02810Male52 YRNINDS0314spouse  No
ND02551Female49 YRNINDS0264spouseLRRK2WILDTYPE for GLY2019 (Bi)No
ND00414Female47 YRNINDS0048spouse  No
ND08724Female53 YR spouse  No
ND10334Female53 YR    No
ND10765Female53 YR    No
ND04339Female52 YR    No
ND05338Female52 YR    No
ND06380Female52 YR    No
ND08005Female52 YR    No
ND09423Female52 YR    No
ND04355Female51 YR    No
ND05405Female51 YR    No
ND06381Female51 YR    No
ND09289Female51 YR    No
ND09883Female51 YR    No
ND09888Female51 YR    No
ND10240Female51 YR    No
ND10274Female51 YR    No
ND10408Female51 YR    No
ND05168Female50 YR    No
ND09026Female50 YR    No
ND09613Female50 YR    No
ND09944Female50 YR    No
ND10446Female50 YR    No
ND10583Female50 YR    No
ND04314Female49 YR    No
ND08020Female49 YR    No
ND10138Female49 YR    No
ND10656Female49 YR    No
ND10249Female49     No
ND04238Female48 YR    No
ND09497Female48 YR    No
ND09672Female48 YR    No
ND09861Female48 YR    No
ND10341Female48 YR    No
ND10444Female48 YR    No
ND10475Female48 YR    No
ND10542Female48 YR    No
ND10635Female48 YR    No
ND10736Female48 YR    No
ND02208Female47 YR    No
ND04356Female47 YR    No
ND06329Female47 YR    No
ND09963Female47 YR    No
ND10265Female47 YR    No
ND01604Female46 YR  LRRK2WILDTYPE for GLY2019 (Bi)No
ND09965Female46 YR    No
ND10860Female46 YR    No
ND04190Male53 YR    No
ND05672Male53 YR    No
ND10470Male51 YR    No
ND04114Male50 YR    No
ND10272Male50 YR    No
ND01605Male49 YR  LRRK2WILDTYPE for GLY2019 (Bi)No
ND10463Male49 YR    No
ND10021Male48 YR    No
ND10546Male48 YR    No
ND10409Male47 YR    No
ND10679Male47 YR    No
ND10871Male47 YR    No
ND03107Male46 YR    No
ND10273Male46 YR    No
ND10298Male46 YR    No
ND10468Male46 YR    No

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