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Induced Pluripotent Stem Cells
To facilitate research on differentiated cell types and other biomedical investigations, the NIGMS Repository offers human induced pluripotent stem cell (hiPSC) lines derived from apparently healthy individuals or from individuals affected with heritable diseases. These hiPSCs were created using a variety of reprogramming techniques*.

Some of the available hiPSC lines were derived from externally submitted iPSC lines, where a distribution stock was made. Others were derived from established LCLs or Fibroblast lines available in the catalog. In addition to QC tests (viability, contamination, karyotyping, microarray genotyping, and microsatellite matches with the parent cell culture), extensive pluripotency characterizations are performed on each NIGMS Repository hiPSC line. Pluripotency characterizations include the following assays:

  • Surface antigen expression
  • Embryoid body formation
  • PluriTest gene expression assay
A complete Certificate of Analysis (CofA) that includes images and quantitative test results is available for each hiPSC line. The CofA PDF specifies which pluripotency characterizations were performed on each hiPSC line.

The Protocol PDFs outline the proper steps for successful handling of the hiPSCs. Additional information is also found on the CofA PDF, including necessary media components, substrates, passage methods, and split ratios.

* For commercial purposes, please note that Limited Use Label Licenses (LULLs) may apply.
Apparently Healthy hiPSC Lines
Records Return:  (22)

12
Catalog IDDescriptionParent LineTransformantLULLGenderAgeRaceBiopsy SourceAffected StatusRelated SamplesCertificate of AnalysisProtocol
GM23392APPARENTLY HEALTHY FETAL TISSUEGM06114Reprogrammed (Retroviral) WARFMale20 FWBlack/African AmericanLungNo910CofA PDFProtocol PDF
GM23396APPARENTLY HEALTHY FETAL TISSUEGM06111Reprogrammed (Retroviral) WARFFemale16 FWBlack/African AmericanSkinNo911CofA PDFProtocol PDF
GM23413APPARENTLY HEALTHY FETAL TISSUEGM06112Reprogrammed (Retroviral) WARFFemale16 FWBlack/African AmericanLungNo911CofA PDFProtocol PDF
GM23450APPARENTLY HEALTHY FETAL TISSUEGM06113Reprogrammed (Retroviral) WARFMale20 FWBlack/African AmericanSkinNo910CofA PDFProtocol PDF
GM23716APPARENTLY HEALTHY FETAL TISSUEGM06111Reprogrammed (Episomal)WARFFemale16 FWBlack/African AmericanSkinNo911CofA PDFProtocol PDF
GM23279APPARENTLY HEALTHY INDIVIDUALNot in RepositoryReprogrammed (Retroviral) IP ACADEMIA JAPANFemale36 YRWhiteSkinNo2997CofA PDFProtocol PDF
GM23476APPARENTLY HEALTHY INDIVIDUALGM04506Reprogrammed (Lentiviral)WARFFemale20 YRWhiteSkinNo732CofA PDFProtocol PDF
GM23720APPARENTLY HEALTHY INDIVIDUALGM02254Reprogrammed (Episomal)WARFFemale22 YRWhitePeripheral veinNo3045CofA PDFProtocol PDF
GM25256APPARENTLY HEALTHY INDIVIDUALWTC11 (6W JY)Reprogrammed (Episomal)IP ACADEMIA JAPANMale30 YRAsianSkinNo3181CofA PDFProtocol PDF
GM25430APPARENTLY HEALTHY INDIVIDUALCV-BReprogrammed (Retroviral) IP ACADEMIA JAPANMale62 YRWhiteSkinNo3238CofA PDFProtocol PDF
GM27717APPARENTLY HEALTHY INDIVIDUALGM03524Reprogrammed (Sendai)Sendai-Cyto TuneFemale67 YRBlack/African AmericanSkinNo CofA PDFProtocol PDF
GM28404APPARENTLY HEALTHY INDIVIDUALGM03234Reprogrammed (Sendai)Sendai-Cyto TuneMale23 YRAmerican Indian/Alaska NativeSkinNo CofA PDFProtocol PDF
GM28907APPARENTLY HEALTHY INDIVIDUALGM07532Reprogrammed (Sendai)Sendai-Cyto TuneFemale16 YROtherSkinNo1057CofA PDFProtocol PDF
GM28978APPARENTLY HEALTHY INDIVIDUALGM00726Reprogrammed (Sendai)Sendai-Cyto TuneFemale26 YRAsianSkinNo CofA PDFProtocol PDF
GM23338PERSONAL GENOME PROJECTGM23248Reprogrammed (Retroviral) IP ACADEMIA JAPANMale55 YRWhiteSkinNo2980CofA PDFProtocol PDF
GM26077PERSONAL GENOME PROJECTGM24143Reprogrammed (Episomal)IP ACADEMIA JAPANFemale74 YRWhite Unknown3140CofA PDFProtocol PDF
GM26105PERSONAL GENOME PROJECTGM24385Reprogrammed (Episomal)IP ACADEMIA JAPANMale45 YRWhite Unknown3140CofA PDFProtocol PDF
GM26107PERSONAL GENOME PROJECTGM24631Reprogrammed (Episomal)IP ACADEMIA JAPANMale33 YRAsian Unknown3150CofA PDFProtocol PDF
GM27730PERSONAL GENOME PROJECTGM27908Reprogrammed (Sendai)Sendai-Cyto TuneMale45 YRWhite Unknown3140CofA PDFProtocol PDF
GM29085PERSONAL GENOME PROJECTGM24694Reprogrammed (Episomal)IP ACADEMIA JAPANMale64 YRChinesePeripheral veinUnknown3150CofA PDFProtocol PDF


Disease-Specific hiPSC Lines
Records Return:  (127) >

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