Principal Investigator, National Institute of General Medical Sciences Human Genetic Cell Repository
Principal Investigator, Congenital Heart Disease Genetic Network Study Biorepository
“Coriell’s long-standing NIGMS Human Genetic Cell Repository and one of our newest – CHD GENES – allow us to distribute biospecimens that we have had for decades, as well as new resources enabled by recent technologies, including induced pluripotent stem cells.”
Dorit S. Berlin, PhD, is principal investigator at Coriell Institute for the National Institute of General Medical Sciences (NIGMS) Human Genetic Cell Repository, a large biobank of cell lines and nucleic acids focusing on inherited disorders. Her responsibilities include managing the day-to-day scientific operations of the biobank, recruiting new samples, identifying new directions for the biobank, and interfacing with governmental project officers.
Dorit is also principal investigator for the Congenital Heart Disease Genetic Network Study (CHD GENES) Biorepository, which is funded through the National Heart, Lung, and Blood Institute (NHLBI). The CHD GENES Biorepository collects biospecimens from individuals with congenital heart disease and extracts DNA from these samples for use in research to identify new genes and new mutations associated with heart disease.
Prior to joining Coriell, Dorit was a postdoctoral scholar at Stanford University, where she worked on scientific curation for the Pharmacogenomics Knowledge Base, synthesizing pharmacogenomic knowledge, generating database and website content, and participating in external collaborations. Dorit also founded and led an education project to create DNATwist (www.dnatwist.org), a web-based pharmacogenomics teaching module. She led the implementation of this material as an online exhibit for the Tech Museum of Innovation in San Jose, CA, now available at http://www.thetech.org/exhibits/online/ugenetics/ from the “Blushing from Alcohol” link.
Dorit earned her undergraduate degree in chemistry from the Massachusetts Institute of Technology and her doctorate in molecular and cell biology from the University of California, Berkeley.