Personalized Medicine at Coriell

Go to Camden-Opioid-Research-Initiative We all have different bodies and different health needs. As we learn more about the ways our genetic differences make each of us unique, the field of personalized medicine (sometimes called precision medicine) aims to use those differences to develop medications and design treatment plans specific to a person’s specific needs.

The benefits of a personalized medicine approach include:

  • Better knowledge to allow for better health decisions
  • Targeted therapies which lead to higher probabilities of success
  • Fewer negative reactions from medications and treatments
  • A focus on prevention and prediction of disease, rather than reaction to it
  • Earlier disease intervention
  • Reduced healthcare costs

The Coriell Institute for Medical Research established itself as a leader in personalized medicine in 2008 with the launch of the Coriell Personalized Medicine Collaborative® (CPMC®), an investigation into the usefulness of genomic information in making every day health decisions. Since its inception, the CPMC has enrolled nearly 8,000 patients, delivered more than 250,000 risk reports and researchers have published a multitude of scientific articles on its findings.

The CPMC remains a model for the ethical, legal, and responsible implementation of best practices in personalized medicine.

Leveraging its expertise gained through the CPMC, Coriell is now turning its focus to study the risk factors for opioid use disorder (OUD), sometimes called opioid dependence. To tackle this, Coriell has partnered with Cooper University Health Care and the Cooper Medical School of Rowan University to form the Camden Opioid Research Initiative (or CORI).

We know that a person’s genetic makeup can put them at greater risk for OUD, but it’s not the only factor. Family medical history and life experiences such as trauma also play a role. CORI researchers are looking into the interplay between genetics and other elements to better understand a person’s risk factor for OUD and to determine if that knowledge can prevent certain patients who rely on these important medications from becoming afflicted in the future and improve outcomes for those already suffering from the disease.