Esan in Nigeria [ESN]

The biomaterials currently available for this population are shown in the table below: 

Population  Esan in Nigeria [ESN]
DNA Sample Panel  MGP00023
Individual DNA Samples  173
Individual Cell Cultures  173

Principal Investigators

  • Pardis Sabeti - Harvard University, Broad Institute, Cambridge, MA
  • Robert Garry - Tulane University, New Orleans, LA 
  • Christian Happi - Redeemers University, Ogun State, Nigeria

Population Description

These cell lines and DNA samples were prepared from blood samples collected in Nigeria. The samples are from a mix of parent- adult child trios and unrelated individuals who identified themselves as Esan. All individuals identified themselves as having four Esan grandparents.

It is important to include a reference to “Nigeria” when describing the source of these samples. Including the name of the country where these samples were collected reinforces the point that the sample set, while not genetically “atypical”, does not necessarily represent all Esan people, whose population history is complex. The population should not be described merely as “African”, “Sub-Saharan African”, “West African”, or “Sierra Leonian”, since each of those designators encompasses many populations with different geographic ancestries.

After the complete descriptor “Esan in Nigeria” has been provided, it is acceptable to use the shorthand label “Esan” or the abbreviation “ESN” in the remainder of the article or presentation. However, the full descriptor for each population should be provided before the shorthand labels are used; this will help to avoid the risks associated with over-generalization of findings.

It may be scientifically appropriate to pool data from these samples with data from other ancestrally related groups, when the data show that the groups have similar allele frequencies. If the groups all have African ancestry, the designation "African ancestry" (abbreviation: AFA) to describe the combined analysis panel is recommended. If only groups very closely related to the Esan have similar allele frequencies, then another abbreviation may need to be used.

Additional guidance about how to refer to the populations can be found at Guidelines for Referring to the Populations in Publications and Presentations.


Policies and Guidelines