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Let Our Expertise Make Your Research a Success
Coriell offers a range of custom research services that have long supported national and international science. Whether you are requesting a cell line for your research studies or submitting DNA samples for genotyping analysis, Coriell is committed to providing you with flexible, innovative, and results-oriented research services. Our laboratories are built to foster scientific collaboration, and your research will benefit from this collaborative environment.
Coriell’s Biobank and Cell Culture Laboratory have established the gold standard in the cryopreservation of biomaterials and the capacity to support varied research worldwide. The diverse collections of biological specimens managed by Coriell offer the scientific community the highest quality specimens, which are necessary for successful research endeavors. Since the first repository – a National Institutes of Health collection – was established at Coriell in 1964, hundreds of thousands of cell lines and DNA samples have been distributed to researchers in 65 countries; more than 7,000 peer-reviewed papers have been published citing over 12,000 biospecimens from the Coriell Biobank.
The service offerings through the Coriell Cytogenetics Laboratory combine conventional and molecular cytogenetic analyses, such as G-banded karyotyping and FISH analysis, with modern cytogenomic technologies capable of capturing chromosome rearrangements at a very high resolution. This genomic service is performed in Coriell’s Genotyping and Microarray Center – one of the nation’s highest-throughput facilities, with systems from Affymetrix and Illumina, and CLIA certification and licensure. If your samples require DNA or RNA isolation before genotyping, Coriell’s Molecular Biology Laboratory can perform this service. Coriell also offers research study design and expertise to support data interpretation and other study requirements.
The Coriell Stem Cell Biobank is committed to providing scientists with the opportunity to bank their pluripotent stem cell lines at the Stem Cell Biobank (SCB), and to develop in-house human induced pluripotent stem (iPS) cell lines for distribution for researchers. The services offered by the SCB includes characterization of iPS cell lines and mouse embryonic stem cell (mESC) lines, such as embryoid body formation, germ-layer specific gene expression, surface antigen testing, and in vitro differentiation.
All services are performed under strict quality systems, including ISO 9001:2008. Throughout the history of the Coriell Institute for Medical Research, the Institute has sought to achieve the highest standards of performance and safety. To this end, the Institute has an Emergency Operations Plans, Exposure Control Policy, and Laboratory Safety Plan. In addition, each department has its own quality control (QC) and quality assurance (QA) procedures. As an experienced manager of biobanks, Coriell has in place systems for detecting and resolving any emerging problems associated with QC. A comprehensive QA/QC program is in place to regulate activities and provide early identification and resolutions.
When you work with Coriell, you are partnering with an institute that prides itself on providing researchers the best in technology and practices. Choose from our research services below; each page offers an overview of our service, contact information, protocols and instructions, and educational materials.
We look forward to working with you.
Key services include establishment of cell lines, preparation of buffy coats (peripheral blood mononuclear cells), growth of cell lines for isolation of nucleic acids and proteins, EBV-transformation of lymphocytes, primary fibroblasts, and differentiated cell lines from biopsy. [ Learn More ]
Key services include banking, cryopreservation, and fail-safe storage of cell lines, DNA, and other biomaterials; online catalog of annotated samples. [ Learn More ]
Key services include karyotype analysis, FISH analysis, and cytogenetic techniques including copy number variation and loss of heterozygosity. [ Learn More ]
Key services include receipt and storage of a variety of samples at optimal temperature, processing of samples to yield DNA and RNA, and reporting of life-cycle of samples [ Learn More ]
Genotyping & Microarray
Key services include Affymetrix platform expression profiling, genome-wide genotyping, copy number variation analysis, and Illumina BeadXpress platform. [ Learn More ]
Key services include DNA and RNA isolation, whole genome amplification (WGA), and Mycoplasma testing. [ Learn More ]
Research Design & Expertise
Key services include protocol and research design, data interpretation, and research support. [ Learn More ]
Cell Lines & DNA
Giving to Coriell
As a non-profit institute, Coriell is fortunate to be engaged in several federally-funded awards. However, we rely on private philanthropy for our more cutting-edge, independent research. Thank you for supporting science!