The most common application of microarrays is gene expression analysis. In this case the interaction between labeled mRNA in a biological sample and complementary DNA probes, which are affixed to the array, allows rapid quantification of the entire transcriptome. Many other types of arrays are possible. More recently, with the completion of the genome sequence, and the continuing work of the HapMap project, SNP genotyping arrays have become available. The data generated by these arrays can not only be used for association studies, but also for copy number analysis.

The Center is outfitted to primarily use arrays that are available from Affymetrix. The Affymetrix GeneChip system is a commercial platform that enables rapid, reproducible, and accurate microarray analysis on a genome-wide scale. The Affymetrix GeneChip platform can be used for both gene expression and genotyping analysis.

At the Coriell Genotyping and Microarray Center we strive to allow you to easily incorporate microarrays into your research and help you get the most out of your data. You provide us with high quality samples and the Center does the rest.