A karyotype is a format to facillitate the study of metaphase chromosome structure.
- Organizes the chromosomes by homologs
- Orders the homologs by size and shape
- Provides an overview of genome
- Detects abnormalities in a single cell
- Detection sensitivity - 5 megabases
- Breakpoint resolution - 5 to 15 megabaes
The data obtained through Karyotype Analysis provide
- Validation of Normal Diploid Karyotypes
- Index of Genomic Stability
- Species Identification
- Analysis of Abnormal Karyotypes Documents
Chromosomal Structural Rearrangements
- Exchange of segments among chromosomes
- Deletion of segments from chromosomes
Changes in Chromosome Number
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