Coriell's cytogenetic research group has three decades of experience with chromosome analysis and, using the most advanced techniques, is fully equipped for bright field and fluorescence microscopy. Digital imaging and analysis are performed using the Applied Imaging Cytovision Ultra and the Vysis Smart Capture Imaging System.
Karyotyping (Human)
standard analysis of metaphase chromosome using G-banding technique
high resolution analysis of prometaphase chromosomes using G-banding and other banding procedures as required
Karyotyping (Mammalian)
standard analysis of metaphase chromosomes from a wide variety of mammalian species, including but not rrestricted to mouse, dog, pig, as well as mouse stem cells
standard metaphase chromosome analysis of various primate species
FISH Analysis
mapping
localization of chromosome break points
estimation of gene copy number in interphase
determination of interphase zygosity of transgenic mice
Comparative Genomic Hybridization Analysis (CGH)
assessment of chromosome loss, gain, or amplification in a sample of genomic DNA by competitive hybridization of two genomes against a target cell
Chromosome Aberration Analysis and Micronucleus Assays
evaluation of genomic damage by a variety of assays to provide genotoxic end points
For more information or to inquire about quotes for any of our products or services, please contact:
Dr. Jay Leonard
Director, Cytogenetics Laboratory
856-757-9704
